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Because your bladder is only designed to hold so much. Once it reaches a point where the tissues are stretched too far, the nerve endings in the bladder send pain signals to your brain. The muscle that is part of the layered bladder wall, the detrusor muscle, starts to contract, increasing the pressure. At that point, break off what you're doing and go!

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8y ago
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Q: Why does it hurt when you hold in your urine?
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