Enzymes are designed to work at their optimum pH. This is the level at which they will work the fastest.
If the pH around an enzyme becomes too high or too low, the protein structure of the enzyme will be denatured. This is a irreversible effect, and the enzyme cannot carry out its function, and is thus useless (you can think of it as dead)
A high pH can denature the enyme meaning it looses it's unque shape and stops working
The stomach secretes protease enzymes that work best at a pH of around 2.
enzyme require an optimum temperature and ph level to be active. temperature at which most enzymes are active is around 35-40 degree celcius. above this temperature the enzyme loses it globular structure and thus the substrate will not be able to bind with it. some enzymes are active in alkali ph while others are active in acidic temperature. but most of the enzymes are active in neutral ph and this helps to maintain its globular structure.
Most enzymes only work in a certain pH range; pH is not dependent on the presence of enzymes, however.
Substrate concentration will affect enzymes because substrates are specific to enzymes. The pH will affect enzymes because certain enzymes will work better in certain pH levels.
Enzymes are very pH-sensitive. Any change in pH results in denaturing of proteins.
Most enzymes work best at a certain pH, however there are some enzymes that can operate over a broad pH range.
The activity of the enzymes depends on the specific pH needed.
at a ph of 13
The activity of intestinal enzymes would likely decrease or become inhibited if the pH of the small intestine remains at 2. This is because the optimal pH for most intestinal enzymes is around neutral or slightly alkaline (pH 6-8). At a pH of 2, the acidic environment may denature or inactivate the enzymes, reducing their ability to catalyze chemical reactions.
every enzyme has specific optimum temperatures and pH. 1. The pH is very specific even a minor change of .5 will cause the enzyme to denature. 2. The temperature is less specific all enzymes will work below the optimum temperature but the reaction will be slower. Above the optimum temperature the enzyme will denature. Note the optimum temperature of the human body is around 37.5 degrees C and the optimum pH is around 7.3.
around 1-2 is the pH of stomach acid