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urea is is the main source of urine
filtration
Passive diffusion - Urea has its own concentration gradient so it will go from an area of high concentration through the cell membrane into an area of lower concentration.
Urea is formed in the kidneys, where it is excreted through the collecting ducts into the ureters and then stored in the urinary bladder until it is voided through the urethra.
Urea is isosmotic to the intracellular fluid of red blood cells, but because the membranes of the blood cells are permeable to urea. Urea enters the cell at a much more rapid rate than other permeable solutes (because of the steep concentration gradient) and the cell fills to it bursts.
During reabsoption most of the water exits the nephron and enters the interstitial fluid. This increases the concentration of ions such as potassium in the nephron. In the collecting duct (at the very end) very little water is left and the concentration of potassium, sodium, etc ions rises (including urea). This is why urine is acidic.
As odd as this may seem, the very purpose of the kidneys is to filter waste materials including urea directly out of the blood. Before urine is isolated and stored by the kidneys and bladder, it is a component of the blood.
A nephron is composed of the Bowman's capsule, the proximal tubule, the loop of the nephron (called the loop of Henle), the distal tubule, and the collecting duct.
urea is is the main source of urine
the concentration of urea should be kept low in the dialysis fluid because urea is harmful for our body if it is not removed.
Glucose and Amino acids because as the concentration of other waste products like urea and CO2 decreases so the CONCENTRATION of glucose and amino acids will increase. NOTE: Only the concentration will increase, that does not mean that their amount also increases
40-50 % of filtered urea is reabsorbed through passive diffusion in the Proximal Convoluted Tubules. Loop of Henle, Distal Convoluted Tubules and Cortical Collecting Ducts are impermeable to urea. But secretion of urea happens in descending Loop of Henle (This helps to maintain the osmotic gradient in the medulla of the Kidney). There is also re-absorption of urea in the medullary collecting ducts.
urea
urea
Urea and ammonia increase because water is reabsorbed from the nephron, making the urea more concentrated.
urea can be mixed with Ca Cl2 @2-4% concentration
# Water is reabsorbed all along the nephron. # Urine becomes hypertonic (salty) because of the loop of Henle and the collecting duct. # Loop of Henle # The descending limb of the loop of Henle can't absorb salt, and the ascending limb can't absorb water. # Salt passively diffuses out of the lower portion of the ascending limb. # The upper part of ascending limb actively transports salt into tissue of the renal medulla. # Increase in salt in the direction of the inner medulla. # Urea leaks from the lower portion of collecting duct and contributes to a high solute (salt) concentration. # Water leaves descending limb of the loop of Henle, returning to the blood. # Urine is hypertonic to blood.