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In glycolysis you get pyruvate (or lactate) as a end product but in gluconeogenesis you get glucose formed from either Fat or Proteins. There are many intermediate steps before pyruvate is formed from Proteins and Fats. So gluconeogenesis cannot be considered as reversal of glycolysis.

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Q: Why gluconeogenesis cannot be considered a reversal of glycolysis even though both pathways share reversible reactions?
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