0
Why grignard reagent cannot be prepared by calcium instead of magnisium?
Wiki User
∙ 11y ago
The beauty of grignard reagents is their relative ease of production, in simple terms just take an alkyl halide add magnesium and stir to get RMgX which can then be reacted further.
The difficulty in using calcium is that the metal itself is less reactive and calcium organometallics are relativelly unstable. Calcium organohalides are also more salt-like and are not as soluble as their Mg counterpart.
This whole area is not that well understood, the mechanism of production of grignards is unclear. Certainly alkylcalcium halides are known but they are difficult to prepare and are described as extremely unrreactive.
If you have access to a library then see:-
Volume 252, Issues 15-17, August 2008, Pages 1516-1531
Recent Advances in Organometallic Chemistry: 2008
Review
Heavy Grignard reagents-Synthesis and reactivity of organocalcium compounds by Matthias Westerhausen
Wiki User
∙ 11y ago
Add your answer:
Earn +20 pts
Why Grignard reagent cannot be prepared by Calcium instead of Magnissium?
The beauty of grignard reagents is their relative ease of production, in simple terms just take an alkyl halide add magnesium and stir to get RMgX which can then be reacted further. The difficulty in using calcium is that the metal itself is less reactive and calcium organometallics are relativelly unstable. Calcium organohalides are also more salt-like and are not as soluble as their Mg counterpart. This whole area is not that well understood, the mechanism of production of grignards is unclear. Certainly alkylcalcium halides are known but they are difficult to prepare and are described as extremely unrreactive.
How can you make a tertiary alcohol from a grignard reagent?
you react the grignard with either an ester, an acid chloride or a ketone to get a tertiary alchohol. if you react a grignard reagent with an aldehyde you get a secondary alcohol and if you react the grignard with formaldehyde (methenal) you get a primary alchohol. same thing happens if u use R-Li instead of a grignard reagant.
What is the impurity formed during the preparation of the Grignard reagent if phenyl bromide was used instead of bromobenzene?
Uses of phenyl in domestic purpose
Why Gold is used instead of calcium to make jewelry?
Gold is a very inert metal. It does not readily react with water or the air(oxygen). Calcium on the other hand is a very reactive metal . If jewellery was made from it , it would react with the skin, air, and water.
Why is it safer to use powdered limestone instead of calcium hydroxide to neutralise acidic soil?
Because limestone is not dangerous when in contact with plants/animals etc. whereas I think calcium hydroxide is an irritant
Why Grignard reagent cannot be prepared by Calcium instead of Magnissium?
The beauty of grignard reagents is their relative ease of production, in simple terms just take an alkyl halide add magnesium and stir to get RMgX which can then be reacted further. The difficulty in using calcium is that the metal itself is less reactive and calcium organometallics are relativelly unstable. Calcium organohalides are also more salt-like and are not as soluble as their Mg counterpart. This whole area is not that well understood, the mechanism of production of grignards is unclear. Certainly alkylcalcium halides are known but they are difficult to prepare and are described as extremely unrreactive.
How can you make a tertiary alcohol from a grignard reagent?
you react the grignard with either an ester, an acid chloride or a ketone to get a tertiary alchohol. if you react a grignard reagent with an aldehyde you get a secondary alcohol and if you react the grignard with formaldehyde (methenal) you get a primary alchohol. same thing happens if u use R-Li instead of a grignard reagant.
What is the impurity formed during the preparation of the Grignard reagent if phenyl bromide was used instead of bromobenzene?
Uses of phenyl in domestic purpose
Why Gold is used instead of calcium to make jewelry?
Gold is a very inert metal. It does not readily react with water or the air(oxygen). Calcium on the other hand is a very reactive metal . If jewellery was made from it , it would react with the skin, air, and water.
Is it correct to ask what did you prepared in the breakfast?
No, it is not correct. The correct phrasing would be "What did you prepare for breakfast?" or "What did you have for breakfast?"
Why is a hot water bath used in grignard reagent production?
It helps to speed up the process. Instead of waiting around a lot longer, you can use the bath to hurry up the process.
Is dinosaur leg bone containing quartz instead of calcium fossils?
yes
Why has RDAs for calcium not been set but instead it has AI levels set?
Sometimes breakfast is unhealthy
What type of fossil is a dinosaur leg bone containing quartz instead of calcium?
It is a trace fossil.
Why you use gravity filtration than evaporation to get calcium carbonate?
why was gravity filtration use instead of evaporation
Why is it safer to use powdered limestone instead of calcium hydroxide to neutralise acidic soil?
Because limestone is not dangerous when in contact with plants/animals etc. whereas I think calcium hydroxide is an irritant
Why are metals such as cobalt used in redox enzymes instead of zinc gallium or calcium?
Because that's the way it is in maynooth!
