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How can the hydrolysis rate of prodrugs be slowed down?
The hydrolysis rate of prodrugs can be slowed down with the usage of sterically hindered esters and the use of long-chain fatty acid esters.
How does the hydrolysis of esters lead to the formation of soap?
Soap is formed by the hydrolysis of fats by lye, not the hydrolysis of esters. The lye strips the 3 fatty acids from the glycerine in the fats and reacts with the free fatty acids producing soap, this process is called saponification.
What has the author Malcolm Frank Goldman written?
Malcolm Frank Goldman has written: 'Acid-catalysed hydrolysis of substituted sterically-hindered benzoate esters' -- subject(s): Hydrolysis, Benzoic acid, Esters
Carboxylic acid can be prepared by?
1- oxidation of alcohols or aldehydes, 2- hydrolysis of nitriles, 3- hydrolysis of esters, 4- reactions of Grignard's reagents with dry ice.
What has the author Cecil Victor King written?
Cecil Victor King has written: 'The mechanism of acid catalysis of ester hydrolysis ..' -- subject(s): Catalysis, Esters, Hydrolysis
What has the author Jameel Ahmad Farooqi written?
Jameel Ahmad Farooqi has written: 'Kinetics of alkaline hydrolysis of some esters'
What has the author B K Abdalla written?
B. K. Abdalla has written: 'The hydrolysis of formate esters in single organic drops'
Base hydrolysis of an ester is called?
SAPONIFICATION
What classes of salts do not undergo hydrolysis?
salts of strong acid and strong base do not undergo hydrolysis
Can ester be hydrolysed to alcohol?
yes, in presence of base, esters can be hydrolysed to alcohol and acid.
How can the hydrolysis rate of prodrugs be accelerated?
If the base hydrolysis mechanism is important, an electron withdrawing group can be attached to the prodrug. If the acid hydrolysis mechanism is important, an electron donating group can be attacked to the prodrug.
Galactose is a product of enzymatic hydrolysis of?
Galactose is obtained from lactose (the milk sugar) after its hydrolysis carried out by the enzyme beta-galactosidase (or lactase) yielding beta-D-glucose and alpha-D-galactose.
