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Each erythrocyt (a blood molecule) is able to carry one molecule of oxygen. In the city your body produces as many erythrocyts as necessary to bring enough oxygen to your cells.

At a high altitude, there's less oxygen in the air and to compensate that, the body needs more erythrocyts. The more erythrocytes you have, the higher is the probability that one will fetch a molecule of oxygen while passing the lungs.

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