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This may be the phenomenon of drug mixing. By this phenomena amoxicillin is mixed with clavulinic acid and the longetivity or the intensity of drug action is increased in that particular area. This increases the action of drug uptil 8 hrs approx. So 8×3=24 hence 3 doses are required daily. But note that the half life remains constant.

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Q: Why is amoxicillin dosed thrice daily even if its half life is 1.5 hours?
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