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Why is testing for Rh antigens and antibodies different from ABO testing?
Wiki User
∙ 12y ago
abo blood group system was discovered in 1901 and rh was discovered in 1940.
Wiki User
∙ 12y ago
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What is the difference between rh incompatibility and abo incompatibility if any?
between ABO and Rh incompatibility
Is tarble strong?
not really since he couldn't beat abo and cado
What color is the tube that blood is drawn for a ABO and Rh factor test?
red top
Transfusion reaction - hemolytic?
DefinitionA hemolytic transfusion reaction is a serious problem that occurs after a patient receives a transfusion of blood. The red blood cells that were given to the patient are destroyed by the patient's own immune system.Alternative NamesBlood transfusion reactionCauses, incidence, and risk factorsBlood is classified into different blood types called A, B, AB, and O.The immune system normally can tell its own blood cells from blood cells from another person. If other blood cells enter your body, your immune system may make antibodies again them. These antibodies will work to destroy the blood cells that the body does not recognize. For example, a person with type A blood makes antibodies against type B blood cells.Another way blood cells may be classified is by Rh factors. People who have Rh factors in their blood are called "Rh positive." People without these factors are called "Rh negative." Rh negative people form antibodies against Rh factor if they receive Rh positive blood.There are also other factors to identify blood cells, in addition to ABO and Rh.Blood that you receive in a transfusion must be compatible. Being compatible means that your body will not form antibodies against the blood you receive. Blood transfusion between compatible groups (such as O+ to O+) usually causes no problem. Blood transfusion between incompatible groups (such as A+ to O-) causes an immune response. This can lead to a very serious transfusion reaction. The immune system attacks the donated blood cells, causing them to burst.Today, all blood is carefully screened. Modern lab methods and many checks have helped make these transfusion reactions very rare.SymptomsBloody urineChillsFainting or dizzinessFeverFlank pain or back painRashSymptoms of transfusion reaction usually appear during or right after the transfusion. Sometimes, they may develop after several days (delayed reaction).Signs and testsThis disease may change the results of these tests:BilirubinCBCCoombs' test, directCoombs' test, indirectFibrin degradation productsHaptoglobinHematocritHemoglobinRBC countSerum creatinineSerum hemoglobinUrinalysisTreatmentTherapy can prevent or treat the severe effects of a hemolytic transfusion reaction. If symptoms occur during the transfusion, the transfusion is stopped immediately. Blood samples from the person getting the transfusion and from the donor may be tested to tell whether symptoms are being caused by a transfusion reaction.Mild symptoms may be treated with the following:Antihistamine drugs (such as diphenhydramine) can treat itching and rash.The pain reliever, acetaminophen can reduce fever and discomfort.Corticosteroids (such as prednisone or dexamethasone) can reduce the immune response.Fluids given through a vein (intravenous) and other medications may be used to treat or prevent kidney failure and shock.Expectations (prognosis)The outcome depends on the severity of the reaction. The disorder may disappear without problems. Or, it may be severe and life threatening.ComplicationsAcute kidney failureAnemiaDiscomfortLung dysfunctionShockCalling your health care providerTell your health care provider if you are having a blood transfusion and you have had a reaction before.PreventionDonated blood is put into ABO and Rh groups to reduce the risk of transfusion reaction.Before a transfusion, patient and donor blood is tested (crossmatched) to see if it is compatible. A small amount of donor blood is mixed with a small amount of patient blood. The mixture is checked under a microscope for signs of antibody reaction.Before the transfusion is given, the health care provider will usually check again to make sure you are receiving the right unit of blood.ReferencesGoodnough L. Transfusion medicine. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier;2007:chap 183.
How does antigens and antibodies determine one's abo blood type?
It is the antigens that determine ones blood group.
Can plasma be used in ABO group?
blood plasma contains no antigens nor antibodies so yes it is universal and can be accepted by anybody.
When the antibodies in the patient's serum attack antigens on the erythrocytes in donor blood this is known as?
When the antibodies in the patient's serum attack antigens on the erythrocytes in donor blood, this is known as red blood cell incompatibility. Patients should receive blood with the same ABO and Rh(D) classification. A and B are dissimilar antigens on the red cells. The immune system recognizes antigens as foreign. O cells do not have A or B antigens.
How is blood typing?
I think it's time for me and you have no idea what I'm talking to my friends are like that you are the same thing to say up with the best yet another example is not the best of the year
ABO blood groups are based on the presence of?
Antigens A & B. If the person inherits just A or B they will be in that blood group, but if they inherit both types of antigens they will be in the AB group, and if they inherit no antibodies they will be in the O group
What determine the ABO blood group in the plasma membrane of rbcs?
The ABO blood group is determined by the presence or absence of specific antigen molecules on the surface of red blood cells. These antigens are determined by the inherited genes from our parents. There are three main types of antigens that determine the ABO blood group: A, B, and O. The combination of these antigens results in different blood types: A, B, AB, and O.
The antigens of the ABO blood group are located in the?
on the surface of the RBC membrane
What was the procedure employed in Serological Testing?
Following ABO comparison, science discovered other proteins in the blood that are more group-specific than the ABO antigens themselves. Known as Rh, Kell and Duffy blood groups, these proteins give scientists the ability to exclude potential fathers at a slightly higher accuracy rate of about 40%. As with ABO testing, serological testing cannot identify the father with certainty but it can exclude those that do not possess the correct blood groups.
A person's ABO blood type is determined by antigens present on the?
gamma globulins
Erythrocyte antigens that determine a person's abo blood type are known as?
agglutinogens
How is it that an incompatible ABO blood group will generate a transfusion reaction the first time a transfusion is given while Rh incompatibility creates a problem the second time?
The antigens of the ABO system are mimicked by bacterial cell walls. So if your body does not actively suppress antibodies to them (because you have them) then antibodies will form over time to the ones you so not have (A or B or both). The rhesus factor (Rh) is not mimicked in nature and so antibodies are not formed in Rh negative people until after an exposure - usually when an Rh negative women carries an Rh positive child. If the person is Rh positive then antibodies will not form no matter what.
How does the Rh factor differ from A B and O antigens?
The Rh factor exhibits normal dominant/recessive patterns. In contrast, the ABO antigens express codominance.
