The cytoplasmic membrane is a poor target for antibacterial medication because of the difficulty in creating an antibiotic that will destroy the cytoplasmic membrane in a bacterium and not destroy the cytoplasmic membrane in a human cell.
Lipid-soluble hormones are able to penetrate through the cell membrane and bind to receptors located inside the cell. Such hormones diffuse across the plasma membrane and target those receptor cells found within the cytoplasm. Lipid-soluble hormones target the cytoplasmic receptors which readily diffuse into the nucleus and act on the DNA, inhibiting and stimulating certain proteins. lipid-insoluble are unable to penetrate through the plasma membrane and function with their target cells in a much different and complex manner. Lipid-insoluble hormones must bind with cell-surface receptors which follow a different path involving a second messenger. The hormone's inability to penetrate the membrane requires a second messenger which translates the outer message and functions within the cell.
Hormones in the bloodstream are able to affect target cells/organs and not other cells/organs because of selective permeability. This means that hormones are only able to pass through the cell membrane of certain cells and organs, and not through the cell membrane of other cells and organs. The cell membrane of the target cells and organs are specialized to allow the hormones to pass through, while the cell membrane of other cells and organs are not specialized and are therefore impermeable to the hormones. This is due to the presence of receptor proteins on the cell membrane of the target cells and organs. These receptor proteins can bind to the hormones and facilitate their entry into the cell. Since these receptor proteins are not present on the cell membrane of other cells and organs, the hormones are unable to bind to them and therefore unable to cross the cell membrane. In addition, hormones can be broken down by enzymes in the bloodstream, which means they can’t reach their target cells and organs if they are exposed to the enzymes. This further ensures that hormones only affect the target cells and organs, and not other cells and organs. In summary, hormones in the bloodstream are able to affect target cells and organs and not other cells and organs because of selective permeability and the presence of receptor proteins on the cell membrane of the target cells and organs. Other cells and organs do not have these specialized receptor proteins and therefore cannot be affected by the hormones.
The target receptor proteins of cells will cause them to affected by a specific protein. These cells are also called "target" cells. Hormones flow via the bloodstream throughout the entire body, but they only affect their specific "target" cells.
because they cannot cross cell membranes
In the plasma membrane of target cells (P - apex)
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Lipid-soluble hormones are able to penetrate through the cell membrane and bind to receptors located inside the cell. Such hormones diffuse across the plasma membrane and target those receptor cells found within the cytoplasm. Lipid-soluble hormones target the cytoplasmic receptors which readily diffuse into the nucleus and act on the DNA, inhibiting and stimulating certain proteins. lipid-insoluble are unable to penetrate through the plasma membrane and function with their target cells in a much different and complex manner. Lipid-insoluble hormones must bind with cell-surface receptors which follow a different path involving a second messenger. The hormone's inability to penetrate the membrane requires a second messenger which translates the outer message and functions within the cell.
target cells
Steroid hormones arelipid-soluble and can dissolve easily into the cell membrane of the target cell to connect with receptors. Protein hormones are water-soluble and connect with receptors at the membrane because it can't diffuse through the membrane.
Target Cell
false
cell membrane
Only target cells have receptors inside cytoplazm (for steroid hormones) or on cell membrane (for protein hormones) that make the hormone active.
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Target cell
The cell membrane contains the membrane proteins that enable a hormone to selectively bind to its plasma membrane. These proteins, such as receptor proteins, are responsible for recognizing and binding to specific hormones, allowing the hormone to exert its effects on the cell.
Hormones in the bloodstream are able to affect target cells/organs and not other cells/organs because of selective permeability. This means that hormones are only able to pass through the cell membrane of certain cells and organs, and not through the cell membrane of other cells and organs. The cell membrane of the target cells and organs are specialized to allow the hormones to pass through, while the cell membrane of other cells and organs are not specialized and are therefore impermeable to the hormones. This is due to the presence of receptor proteins on the cell membrane of the target cells and organs. These receptor proteins can bind to the hormones and facilitate their entry into the cell. Since these receptor proteins are not present on the cell membrane of other cells and organs, the hormones are unable to bind to them and therefore unable to cross the cell membrane. In addition, hormones can be broken down by enzymes in the bloodstream, which means they can’t reach their target cells and organs if they are exposed to the enzymes. This further ensures that hormones only affect the target cells and organs, and not other cells and organs. In summary, hormones in the bloodstream are able to affect target cells and organs and not other cells and organs because of selective permeability and the presence of receptor proteins on the cell membrane of the target cells and organs. Other cells and organs do not have these specialized receptor proteins and therefore cannot be affected by the hormones.