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Why is the endoplasmic reticulum important in the production of insulin?
Wiki User
∙ 13y ago
Endoplasmic reticulum (ER) or more specific rough endoplasmic reticulum is important due to the presence of ribosomes on the surface of ER.
The protein synthesis takes place in the ribosomes but once its "completed" it moves within the interior of the ER.
Now ER is important because although the protein synthesis is done still some modifications is required to activate it. A portion of modification is done inside the ER where proteins ( eg. Insulin) are a step closer for activation.
hope this helps :)
Wiki User
∙ 13y ago
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What is a internal organ that produces insulin?
pacreas The "pancreas" is and ORGAN. Organelles and organs are two different things. The organelles responsible for the production of insulin are the nucleus, rRNA, golgi, and rough endoplasmic reticulum.
Which organelles are responsible for the synthesis insulin?
Rough endoplasmic reticulum. The peptide bonds are actually formed by an structure called a ribosome. This is capable of making peptide bonds whether it is attached to the endoplasmic reticulum or free floating in the cytoplasm - but it isn't a organelle. However, the rough endoplasmic reticulum is a membrane-bound organelle which has a surface which is studded with ribosomes.
What is the targeting pathway of insulin?
Endoplasmic Reticulum --> Golgi Apparatus --> outside the cell
Which proteins are synthesized by bound ribosomes?
Yes, where? The first R in 'RER' stands for rough as in 'rough endoplasmic reticulum'. Compare this to 'SER' - smooth endoplasmic reticulum. Yes, the rough designation reflects the existence of endoplasmic bound ribosome entities/particles that are the main sites of cellular protein synthesis.
Why do some cells of the human pancreas have up to 100 times the amount of endoplasmic reticulum as other parts of the body?
The pancreas secretes the hormones insulin, glucagon, and somatastatin, and the digestive enzymes, lipase, protease, and amylase. Proteins that will be secreted by the cell are produced by the ribosomes on the rough endoplasmic reticulum. Therefore, cells that secrete proteins have a large amount of rough endoplasmic reticulum.
What would be the effects of adding the sequence KDEL to insulin?
KDEL an amino acid sequence which signals that a protein belongs in the endoplasmic reticulum. Attaching it to insulin would cause the insulin to be retained within the endoplasmic reticulum.
What is a internal organ that produces insulin?
pacreas The "pancreas" is and ORGAN. Organelles and organs are two different things. The organelles responsible for the production of insulin are the nucleus, rRNA, golgi, and rough endoplasmic reticulum.
What is the route of insulin from its production to its exit from the cell?
The route of the insulin from its production to its exit from the cell is at the pancreatic cells. This is then secreted in the bloodstream.
Which organelles are responsible for the synthesis insulin?
Rough endoplasmic reticulum. The peptide bonds are actually formed by an structure called a ribosome. This is capable of making peptide bonds whether it is attached to the endoplasmic reticulum or free floating in the cytoplasm - but it isn't a organelle. However, the rough endoplasmic reticulum is a membrane-bound organelle which has a surface which is studded with ribosomes.
What is the targeting pathway of insulin?
Endoplasmic Reticulum --> Golgi Apparatus --> outside the cell
Which proteins are synthesized by bound ribosomes?
Yes, where? The first R in 'RER' stands for rough as in 'rough endoplasmic reticulum'. Compare this to 'SER' - smooth endoplasmic reticulum. Yes, the rough designation reflects the existence of endoplasmic bound ribosome entities/particles that are the main sites of cellular protein synthesis.
Why do some cells of the human pancreas have up to 100 times the amount of endoplasmic reticulum as other parts of the body?
The pancreas secretes the hormones insulin, glucagon, and somatastatin, and the digestive enzymes, lipase, protease, and amylase. Proteins that will be secreted by the cell are produced by the ribosomes on the rough endoplasmic reticulum. Therefore, cells that secrete proteins have a large amount of rough endoplasmic reticulum.
What substances are produced at the surface of the Endoplasmic Reticulum of a cell?
Pepsin is produced by cells lining the stomach and released into the stomach cavity. Insulin is made by pancreatic cells & released into the bloodstream.
Why are ribosomes attached to the endoplasmic reticulum?
Rough Endoplasmic ReticulumThere are two types of Endoplasmic Reticulum:1) Rough ER which has Ribosomes attached to it on the sides and walls. Giving it a "rough" look2)Smooth ER which has no ribosomes. Giving it a "smooth" look
What cell structure produces enzymes in the pancreas?
While the pancreas produces insulin, insulin is a hormone not a digestive enzyme. The enzymes secreted by the pancreas are proteases, lipase, trypsin and amylase.
What is the of the endoplasmic reticulum?
here are several definitions i found on dictionary.comDictionary.com Unabridged (v 1.1) - Cite This Source - Share Thisendoplasmic reticulum-noun Cell Biology. a network of tubular membranes within the cytoplasm of the cell, occurring either with a smooth surface (smooth endoplasmic reticulum) or studded with ribosomes (rough endoplasmic reticulum), involved in the transport of materials.American Heritage Dictionary - Cite This Source - Share This endoplasmic reticulumn. A membrane network within the cytoplasm of cells involved in the synthesis, modification, and transport of cellular materials.endoplasmic reticulum (ěn'də-plāz'mĭk) Pronunciation KeyAn organelle consisting of a network of membranes within the cytoplasm of eukaryotic cells that is important in protein synthesis and folding and is involved in the transport of cellular materials. The endoplasmic reticulum can be continuous in places with the membrane of the cell nucleus. The function of the endoplasmic reticulum can vary greatly with cell type, and even within the same cell it can have different functions depending on whether it is rough or smooth. ◇ The rough endoplasmic reticulum is a series of connected flattened sacs that have many ribosomes on their outer surface. Rough endoplasmic reticulum synthesizes and secretes serum proteins (such as albumin) in the liver, and hormones (such as insulin) and other substances (such as milk) in the glands. ◇ The smooth endoplasmic reticulum is tubular in form and is involved in the synthesis of phospholipids, the main lipids in cell membranes. Smooth endoplasmic reticulum is the site of the breakdown of toxins and carcinogens in the liver, the conversion of cholesterol into steroids in the gonads and adrenal glands, and the release of calcium ions in the muscles, causing muscle contraction. The smooth endoplasmic reticulum also transports the products of the rough endoplasmic reticulum to other cell parts, notably the Golgi apparatus. See more at cell.my knowlage: an organelle found inside of some cells often abbreaviated as ER. A rough ER is an ER with ribosomes stuck to it, and a smooth ER is one without ribosomes. the ER is often found around the nucleus. it can sometimes be confused with the Golgi complex because of their similar looking shape.this is alot of info!!!!!hope it helps!!!!!!
Diabetes is a result of the insufficient production of what?
insulin in the pancreas
