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In the mitochondria
No. Mutations are changes in a genomic sequence. Blue eyes are not changes.
Almost all eukaryotic organism have two types of Genetic material. Genomic DNA and mitochondrial DNA. Mitochondria itself a seperate bacteria, in evolution they are engulfed by the host cell. Mitochondria provides(synthesis) the energy needed by host cell. In turn, the host cell protects the mitochondria from the environmental hazards. The relationship is symbiotic in nature. If we ate food or antibiotics which affects the bacteria, there is a chance that will affects the mictochondrial DNA too.
Statistically speaking, the fidelity of DNA polymerases is very high and they usually make 1 mistake for every 1000000000 base pairs that they add to a growing DNA strand. However, there are many external methods of inducing mutations, most notably by chemicals and radiation. Therefore it is estimated that the genomic DNA mutation rate per generation for humans is one in 40000000 base pairs. However, human mitochondrial DNA curiously carries a much higher mutation rate per generation of about 1 in 37000 to 1 in 333000 base pairs. For the mutation rates of other organisms, follow the link below.
Mitochondria are organelles found in mammalian cells that generate chemical energy. They are important in a process called oxidative phosphorylation which ultimately results in energy generation. They have their own DNA that is separate from the genomic DNA. They are often referred to as the powerhouse of the cell
If the rate of repair lags behind the rate of mutation, the cell may accumulate DNA damage that can result in genomic instability. This can lead to an increased risk of developing cancer or other diseases.
Genomic Medicine Institute was created in 2005.
Genomic Standards Consortium was created in 2005.
Genomic library
Genome chips are miniaturized plates containing hundreds of microscopic wells on their surface. These wells contain DNA probes. DNA probes are basically stretches of cDNA from a particular genome. When genomic DNA isolated from an organism is allowed to interact with the cDNA probes, come probes bind to the genomic DNA while others do not (depending on complementarity. A laser light is used to read each well and look at what sequences are bound. This information is valuable to scientists who can determine changes in gene expression based on the information obtained from a gene chip
A map of the distribution of cloned genomic DNA from genomic clone libraries shows the physical location of different DNA fragments within the genome. This type of map is used to study genetic organization, identify genes, and analyze specific regions of interest within the genome. It helps researchers understand the genomic structure and function of an organism.
"Molecular clocks" can be used to estimate the time at which two lineages diverged. Often, the calibration of the clock uses fossil evidence to gauge a timeframe for the existence of a common ancestor of a number of lineages. From this, an average mutation rate can be calculated. This average mutation rate can then be used to estimate the timeframe for further branching points in the genealogy of the lineages in question.For instance, fossil evidence could be used to establish a timeframe for the existence of a common ancestor to all great apes. By dividing the sum of all differences in a particular genomic sequence for all great apes by the time between then and now, we get an average rate. We can then take the differences between that genomic sequence in men and Neanderthals to estimate when Neanderthals diverged from us.