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Because, anatomically, 70% of peripheral globe is composed of glandular glands. As prostate cancer is a adenocarcinoma (involving the glands of prostate), and peripheral lobe is mostly of glands, that is why it is more common in this lobe.

On the other hand, this is the main target of male sexual hormones, which increases the chances for prostate cancer.

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Q: Why prostate cancers are common in peripheral zone of prostate gland?
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