Because human DNA is so very long (with up to 80 million base pairs in a chromosome) it unzips at multiple places along its length so that the replication process is going on simultaneously at hundreds of places along the length of the chain. Eventually these areas run together to form a complete chain. In humans, DNA is copied at about 50base pairs per second. The process would take a month (rather than the hour it actually does) without these multiple places on the chromosome where replication can begin.
Replication of human chromosomes is a complex and time-consuming process because there are 46 chromosomes in each human cell, and each chromosome contains a large amount of DNA. Additionally, the replication process involves multiple steps and requires the coordination of many molecular machinery and enzymes. Furthermore, the DNA replication process must be highly accurate to prevent errors and maintain the integrity of the genetic material. All these factors contribute to the length of time required for replication.
G1 - 46 single-chromatid chromosomes = 46 DNA molecules; s - replication takes place, so that at the end of S and in G2 - 46 double-chromatid chromosomes = 92 DNA molecules
D-loop replication mostly takes place during DNA-replication. But it also can occur in telomeres and mitochondria.
genomic replication, or DNA replication, is performed by multiple enzymes that together are called a replicase. This replication takes place within the nucleus of a cell
Replication does not take place during mitosis. It takes place before meiosis begins.
In humans there are 23 pairs of chromosomes in a diploid cell (a normal body cell e.g. a skin cell) However there are just 23 single chromosomes in a haploid cell (a sex cell e.g. a sperm) this is because when fertilisation takes place the embryo has a total of 46 chromosomes, as it takes both haploid cells, making it genetically identical to both it's mother and father, and making it a diploid cell.
G1 - 46 single-chromatid chromosomes = 46 DNA molecules; s - replication takes place, so that at the end of S and in G2 - 46 double-chromatid chromosomes = 92 DNA molecules
DNA replication takes place in NUCLEUS
The DNA replication machinery initially assembles and begins replication at the origin of replication. It contains high levels of AT base pairs for easier unzipping and there's usually one per bacteria chromosome, several for archaea chromosome, and many many more for eukaryotic linear chromosomes.
Chromosomal replication and DNA replication takes place in S-phase.
Replication is the process of copying genetic material, such as DNA or RNA, to produce an identical or similar copy. In biology, it plays a crucial role in cell division, growth, and repair. Replication ensures that genetic information is passed on accurately from one generation to the next.
in a direction opposite to that of the replication fork
In the same directions of the replication fork
Nucleus has various functions, but its distinctive feature is that it holds the DNA/chromosomes. Additionally to DNA replication, transcription of DNA into mRNA also takes place in the nucleus.
Metaphase is the stage of mitosis in which the all of the cell's chromosomes align along the equator of the cell. It is the final stage before the cell splits into two daughter cells.
DNA replication takes place when preceding interphase.
D-loop replication mostly takes place during DNA-replication. But it also can occur in telomeres and mitochondria.
When DNA replication takes place without subsequent cell division, polytene chromosomes may result. These are giant chromosomes comprised of multiple chromatids (identical chromosome copies) arranged together like strands of a large cable. They are commonly found in the salivary glands of the fruit fly (Drosophila melanogaster) and are regions of active transcription.