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Actually you can, but it's important to understand why the literature tells you not to.

The reason is that the patch stays applied in the same spot for 48-72 hours, depending on the patient. During this period, the skin in that area doesn't have time to breathe, so keeping it constantly covered will cause skin problems over time.

The trick to using the same spot is to take off the old patch, clean and dry the skin area, then let it breathe for about 2-4 hours before putting on another patch. That's usually enough time before you start feeling withdrawals, and even if you do feel a twinge, you can take some Percocet or other breakthrough meds to compensate while the new patch dose ramps up.

Personally, I used both my biceps; I'd put a new patch on my left bicep when I took the old one off my right one.

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Q: Why shouldn't you put Fentanyl patches in the same place twice?
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