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When will a generic Imitrex injection be available?
From http://www.spectrumpharm.com/sumatriptan.html on 3July2008: On October 2004, we filed with the FDA an abbreviated new drug application (ANDA) with a paragraph IV certification, for sumatriptan succinate injection 6mg/0.5mL, seeking approval to engage in the commercial manufacture, sale, and use of the sumatriptan succinate injection product in the United States. Sumatriptan succinate is marketed by GlaxoSmithKline under the brand name Imitrex®. On February 18, 2005, GlaxoSmithKline filed a lawsuit against Spectrum Pharmaceuticals in the United States District Court in the District of Delaware, alleging infringement of the Imitrex® patent. In November 2006, Spectrum and GSK reached an agreement to settle the patent litigation relating to sumatriptan injection. The terms of the confidential agreement provide that Spectrum may exclusively distribute authorized generic versions of certain sumatriptan injection products in the United States with an expected launch during GSK's sumatriptan pediatric exclusivity period which begins on August 6, 2008, but with the launch occurring not later than November 6, 2008. Spectrum will launch sumatriptan injection through its partner for the sale and distribution of the drug, Par Pharmaceutical Companies, Inc.
Is Sumatriptan suitable for vegans?
Sumatriptan has been tested on animals.
What is ammonium succinate?
what is ammonium succinate? An amino acid
How malonate inhibit the conversion of succinate to fumarate?
Malonate is a competitive inhibitor of succinate dehydrogenase, the enzyme responsible for converting succinate to fumarate in the citric acid cycle. Malonate resembles succinate and competes for the active site of succinate dehydrogenase. As a result, malonate binds to the enzyme and prevents succinate from binding, inhibiting the conversion of succinate to fumarate.
DOES sumatriptan affect depo provera?
There are no known drug interactions between sumatriptan and depo provera
Differences between succinate and succinate malonate?
Malonate is a competitive inhibitor preventing the substrate succinate from binding to the enzyme. The structure of succinate is comparable to that of malonate but for the ability for malonate to bind to an enzyme but then cannot further act on it creating a nonproductive complex.
What is Malonic acids role with respect to succinate dehydrogenase?
Malonic acid is a competitive inhibitor of succinate dehydrogenase.
Where does oxidative enzyme exist?
All through the Citric Acid Cycle. Succinate dehydrogenase oxidizes succinate.
How long does Doxylamine succinate stay in your body's system?
Is dolxylamine succinate a drug they look for when drug testing.
Is there a generic for sumatriptan in the US?
Yes. Since late 2008. See http://nervous-system.emedtv.com/sumatriptan/generic-sumatriptan.html
Is doxylamine succinate an nsaid?
no
Metoprolol tartrate and metoprolol succinate are examples of what two things?
Tartrate is the generic for Lopressor. Succinate is the generic for Toprol XL.
