Will there be a prison break series 5?

PB season 4 returns on Fri, Apr 17, 2009 in the US (Tue, Apr 21st UK) to complete its final season with a 5 week run ending with a double episode on Fri, May 15th (US). FOX did not renew Prison Break for a fifth season, so no Prison Break 5. The series will end when season 4 has completed the last 6 of its 22 episodes.