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This can be a dangerous combination of medications to take. Please consult with your physician before taking either of these medications.

I have been on methadone for 10 years and on Seroquel for 6 and I am just fine. I did find out however that if I don't take my methadone or some sort of opiate, and I still take my Seroquel I get horrible Restless Leg Syndrome. I was off methadone for a few months and it was hell. I got back on my methadone and was find. Now I am detoxing from methadone and as the dose lowers I am getting Restless Leg Syndrome again which upsets me because I want off of the methadone but need Seroquel for sleep. I am in a quandry.

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10y ago
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14y ago

No, you will not die if you take as prescribed. One fourth of my patients at the Methadone clinic I work at are on Seroquel. It is safest to let your prescribing Doctor know you are on Methadone so he can adjust dose accordingly. Like any drug, if abused, there is danger.

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14y ago

It will help some simply because it will calm you down and also help you sleep which is usually pretty hard to do when withdrawing from anything. But I would recommend suboxone instead which is actually partially an opiate so it will help fill the void in your opiod recepters which is the reason you would be withdrawing in the first place hope this helped!!

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10y ago

Seroquel is an anti-psychotic drug and is often taken as a sleep aid. But when mixed with methadone, the two mix for a stronger sensation, as the seroquel intensifies the effects of methadone.

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14y ago

It can be very fatal when these two medications are mixed together. Please consult your physician before taking this combination of medications.

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11y ago

nothing

seroquel and methadone are prescribed together quite frequently.

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11y ago

is it dangerousfor me to take 50 mgs of seroquel with 110 mgs of methadone

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Q: Will you die if you take methadone with seroquel?
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