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Benadryl (Diphenhydramine), has been reported to cause false positives for benzodiazepines (such things as Xanax, Valium), PCP and tricyclic anti-depressants. The false positives occur using the screening-type tests (sticks, cups, etc) but confirmatory tests using GC/MS should clear any false positive.

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14y ago
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9y ago

You shouldn't, unless you're an Olympic athlete; Benadryl is a common OTC drug so it's not normally tested for. The Olympics tests for about a thousand things and Benadryl is one of them.

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Q: Will you fell a drug test if you take benadryl?
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