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Not particularly - the B cell is the class of lymphocyte that is responsible for making antibodies and a certain subclass of B cells are the "memory cells" that retain the ability to make useful and needed antibodies in case of exposure to the same pathogen again.

A vaccination is not likely to do a person with B cell deficiencies much good - they can mount a weak T cell based immune response, but without B cells to activate the T cells and modulate the immune response, it will be pretty weak.

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Q: Would vaccinations help people with B cell deficiencies?
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