Fanconi syndrome is a disorder of the kidney tubes in which certain substances normally absorbed into the bloodstream by the kidneys are released into the urine instead.
Alternative NamesDe Toni-Fanconi syndrome
Causes, incidence, and risk factorsFanconi syndrome can be caused by faulty genes, or it may result later in life due to kidney damage. Sometimes the cause of Fanconi syndrome is unknown.
Common causes of Fanconi syndrome in children are genetic defects that affect the body's ability to break down certain compounds such as:
Cystinosis is the most common cause of Fanconi syndrome in children.
Other causes in children include:
In adults, Fanconi syndrome can be caused by various things that damage the kidneys, including:
Laboratory tests may show that too much of the following substances may be lost in the urine:
Loss of these substances can lead to a variety of problems. Further tests and a physical exam may show signs of:
Many different diseases can cause Fanconi syndrome. The underlying cause and its symptoms should be treated as appropriate.
Expectations (prognosis)The prognosis depends on the underlying disease.
Calling your health care providerCall your health care provider if you have dehydration or muscle weakness.
ReferencesSeifter JL. Potassium disorders. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 118.
Fanconi syndrome is a disorder of the kidney tubes in which certain substances normally absorbed into the bloodstream by the kidneys are released into the urine instead.
Alternative NamesDe Toni-Fanconi syndrome
Causes, incidence, and risk factorsFanconi syndrome can be caused by faulty genes, or it may result later in life due to kidney damage. Sometimes the cause of Fanconi syndrome is unknown.
Common causes of Fanconi syndrome in children are genetic defects that affect the body's ability to break down certain compounds such as:
Cystinosis is the most common cause of Fanconi syndrome in children.
Other causes in children include:
In adults, Fanconi syndrome can be caused by various things that damage the kidneys, including:
Laboratory tests may show that too much of the following substances may be lost in the urine:
Loss of these substances can lead to a variety of problems. Further tests and a physical exam may show signs of:
Many different diseases can cause Fanconi syndrome. The underlying cause and its symptoms should be treated as appropriate.
Expectations (prognosis)The prognosis depends on the underlying disease.
Calling your health care providerCall your health care provider if you have dehydration or muscle weakness.
ReferencesSeifter JL. Potassium disorders. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa: Saunders Elsevier; 2007:chap 118.
Reviewed ByReview Date: 02/05/2012
Melissa B Bleicher, MD, Division of Renal, Electrolyte, and Hypertension, Hospital of the University of Pennsylvania, Philadelphia, PA. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.
does fanconi syndrome lead to cancer
Fanconi's syndrome can be reversible. Fanconi's syndrome caused by kidney transplantation usually reverses itself within the first year after transplant surgery. When caused by a toxin in the environment, Fanconi's syndrome generally can.
Fanconi's syndrome affects the kidney
Fanconi's syndrome can be caused by a variety of genetic defects and by certain environmental assaults. The genetic diseases known to give rise to Fanconi's syndrome are cystinosis (the most common cause in children).
Fanconi's syndrome caused secondarily by the genetic diseases galactosemia, glycogen storage disease, hereditary fructose intolerance, and tyrosinemia is prevented by appropriate dietary restrictions to treat the genetic disease.
Fanconi's syndrome is best treated by attacking the underlying cause whenever possible. For example, when cystinosis is treated with the drug cysteamine to lower cystine levels in the body or Wilson disease is treated with.
Diagnosis of Fanconi's syndrome can be made by urine and blood tests. It is also important to find the underlying cause to decide on the best treatment. Other symptoms specific to a particular patient will point to other useful diagnostic tests.
A rare disorder caused by vitamin D deficiency or exposure to heavy metals.
Proximal renal tubular acidosis (type 2) is caused by hereditary diseases, such as Fanconi's syndrome, fructose intolerance, and Lowe's syndrome.
Guido Fanconi was born in 1892.
Guido Fanconi died in 1979.
I'm guessing there is none, that fanconi anemia is the scientific name, and that the common name is FA.