Metabolic syndrome is a name for a group of risk factors that occur together and increase the risk for coronary artery disease, stroke, and type 2 diabetes.
Alternative NamesInsulin resistance syndrome; Syndrome X
Causes, incidence, and risk factorsMetabolic syndrome is becoming more and more common in the United States. Researchers are not sure whether the syndrome is due to one single cause, but all of the syndrome's risk factors are related to obesity.
Metabolic syndrome is associated with many conditions and risk factors. The two most important risk factors are:
Insulin helps blood sugar (glucose) enter cells. If you have insulin resistance, your body doesn't respond to insulin, and blood sugar cannot get into cells. As a result, the body produces more and more insulin. Insulin and blood sugar levels rise, affecting kidney function and raising the level of blood fats, such as triglycerides.
Other risk factors include:
According to the American Heart Association and the National Heart, Lung, and Blood Institute, metabolic syndrome is present if you have three or more of the following signs:
Tests that may be done to diagnose metabolic syndrome include:
The goal of treatment is to reduce your risk of Heart disease and Diabetes. Your doctor will recommend lifestyle changes or medicines to help reduce your blood pressure, LDL cholesterol, and blood sugar.
Recommendations include:
Some people may need daily low-dose aspirin.
People who smoke should quit.
Expectations (prognosis)People with metabolic syndrome have an increased long-term risk for developing cardiovascular disease and type 2 diabetes.
ComplicationsCall your health care provider if you have signs or symptoms of this condition.
PreventionPreventing (and managing) the condition involves:
Lichtenstein AH, Appel LJ, Brands M, et al. Diet and lifestyle recommendations revision 2006: a scientific statement from the American Heart Association Nutrition Committee. Circulation. 2006;114:82-96.
Lakka T, Laaksonen DE. Physical activity in prevention and treatment of the metabolic syndrome. Appl Physiol Nutr Metab. 2007;32(1):76-88.
Grundy SM, Cleeman JI, Daniels SR, Donato KA, Eckel RH, Franklin BA, et al. American Heart Association; National Heart, Lung, and Blood Institute. Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute Scientific statement. Cardiol Rev. 2005;13:322-327.
Mahley RW, Weisgraber KH, Bersot TP. Disorders of Lipid Metabolism. In: Kronenberg HM, Melmed S, Polonsky KS, Larsen PR, eds. Williams Textbook of Endocrinology. 11th ed. Philadelphia, Pa: Saunders Elsevier; 2008:chap 36.
Metabolic syndrome is a name for a group of risk factors that occur together and increase the risk for coronary artery disease, stroke, and type 2 diabetes.
Alternative NamesInsulin resistance syndrome; Syndrome X
Causes, incidence, and risk factorsMetabolic syndrome is becoming more and more common in the United States. Researchers are not sure whether the syndrome is due to one single cause, but all of the risks for the syndrome are related to obesity.
The two most important risk factors for metabolic syndrome are:
Other risk factors include:
Peole who have metabolic syndrome often have two other problems that can either cause the condition or make it worse:
According to the American Heart Association and the National Heart, Lung, and Blood Institute, metabolic syndrome is present if you have three or more of the following signs:
Tests that may be done to diagnose metabolic syndrome include:
The goal of treatment is to reduce your risk of heart disease and diabetes. Your doctor will recommend lifestyle changes or medicines to help reduce your blood pressure, LDL cholesterol, and blood sugar.
Recommendations include:
Some people may need to take daily low-dose aspirin.
People who smoke should quit.
Expectations (prognosis)People with metabolic syndrome have an increased long-term risk for developing cardiovascular disease and type 2 diabetes.
ComplicationsCall your health care provider if you have signs or symptoms of this condition.
PreventionPreventing (and managing) the condition involves:
Mahley RW, Weisgraber KH, Bersot TP. Disorders of Lipid Metabolism. In: Kronenberg HM, Melmed S, Polonsky KS, Larsen PR, eds. Williams Textbook of Endocrinology. 11th ed. Philadelphia, Pa: Saunders Elsevier; 2008:chap 36.
Alberti KG, Eckel RH, Grundy SM, Zimmet PZ, Cleeman JI, Donato KA, et al. Harmonizing the metabolic syndrome: a joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention: National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; and International Association for the Study of Obesity. Circulation. 2009;120:1640-1645.
Rosenzweig JL, Ferrannini E, Grundy SM, Haffner Sm, Heine RJ, Horton ES, et al. Primary prevention of cardiovascular disease and type 2 diabetes in patients at metabolic risk: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab. 2008; 93:3671-3689.
Reviewed ByReview Date: 06/28/2011
Ari S. Eckman, MD, Division of Endocrinology, Diabetes and Metabolism, Trinitas Regional Medical Center, Elizabeth, NJ. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.
Metabolic syndrome is a set of medical risk factors. These factors determine the risk of certain diseases.
Metabolic syndrome is actually a combination of syndromes. For more information, check out www.mayoclinic.com/health/metabolic%20syndrome/DS00522, the mayo clinic's site.
here is a website to learn more about metabolic syndrome. I hope this helps you on your quest for answers http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0004546/
It has been estimated that just over 40% of the US population over the age of 50 have metabolic syndrome. This number is growing!
Some causes of metabolic syndrome include gaining too much weight, smoking, not getting exercise, and getting older.http://www.medicinenet.com/metabolic_syndrome/page2.htm
Say Ahh - 2010 Prostate Health and Metabolic Syndrome 1-14 was released on: USA: 4 January 2011
Metabolic syndrome is a health disorder that leads to hypertension, diabetes, heart disease and stroke. Its main cause is due to obesity, which stems from poor diet and exercise activity.
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There are a variety of metabolic syndromes a doctor may look for if symptoms present. They would usually do a symptom history and the appropriate blood tests.
Some diabetes medications, such as metformin, are used in people without diabetes to treat other conditions, such as metabolic syndrome or polycystic ovarian syndrome.
There are several alternative methods to treat metabolic syndrome. Some doctors recommend changing to a more healthy diet and exercising more often. There are also drugs that can treat the disease that includes various high blood pressure medicines, cholesterol medicines, and even low dose aspirin.
Zellweger syndrome is diagnosed by measuring metabolic compounds in blood samples from patients. Various fatty acids, plasmalogens, pipecolic acid, and bile acid intermediates are usually studied