Thrombotic thrombocytopenic purpura (TTP) is a blood disorder that causes blood clots to form in small blood vessels around the body, and leads to a low platelet count (thrombocytopenia).
See also: Hemolytic-uremic syndrome
Alternative NamesTTP
Causes, incidence, and risk factorsThis disease may be caused by the lack of an enzyme (a type of protein) that is involved in blood clotting. Not having enough of this enzyme causes clotting to occur. As the platelets clump together in these clots, fewer platelets are available in the blood in other parts of the body to help with clotting. This can lead to bleeding under the skin and purple-colored spots called purpura.
In many cases, the disorder is passed down through families (inherited). The condition also may be related to:
Plasma exchange (plasmapheresis) is used to remove the abnormal antibody from the blood and replace the missing enzyme.
First, you will have your blood drawn as if you were donating blood.The plasma portion of the blood will be passed through a cell separator. The remaining portion of the blood will be saved. Plasma will be added to it, and the blood will be returned to you through a transfusion.
This treatment is repeated daily until blood tests show improvement. People who do not respond to this treatment, or who have frequent recurrences, may need to have surgery to remove their spleen. Or, they may need to get drugs that suppress the immune system (such as corticosteroids).
Expectations (prognosis)Plasma exchange has improved the outcome of this disease. Most patients now recover completely. However, some people can die from this disease, especially if it is not found immediately. In people who don't recover, this condition can become long-term (chronic).
ComplicationsCall your health care provider if you have any unexplained bleeding.
PreventionBecause the cause is unknown, there is no known way to prevent this condition.
ReferencesSchafer A. Hemorrhagic disorders: Abnormalities of platelet and vascular function. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa:Saunders Elsevier;2007:chap 179.
Thrombotic thrombocytopenic purpura (TTP) is a blood disorder that causes blood clots to form in small blood vessels around the body, and leads to a low platelet count (thrombocytopenia).
See also: Hemolytic-uremic syndrome
Alternative NamesTTP ADAMTS13
Causes, incidence, and risk factorsThis disease may be caused by a lack of, or problems with, a certain enzyme (a type of protein) that is involved in blood clotting. These changes cause clotting to occur in an abnormal way.
In some cases, the disorder is passed down through families (inherited) and patients are born with naturally low levels of this enzyme. This condition also may be related to:
Plasma exchange (plasmapheresis plus infusion of donor plasma) is used to remove the antibodies that are affecting clotting from the blood and also replace the missing enzyme.
This treatment is repeated daily until blood tests show improvement.
People who do not respond to this treatment or whose condition often returns may need to:
Plasma exchange has greatly improved the outcome of this disease. Most patients now recover completely. However, some people die from this disease, especially if it is not found immediately. In people who don't recover, this condition can become long-term (chronic).
ComplicationsCall your health care provider if you have any unexplained bleeding.
PreventionBecause the cause is unknown, there is no known way to prevent this condition.
ReferencesMcCrae KR, Sadler JE, Cines DB. Thrombotic thrombocytopenic purpura and the hemolytic uremic syndrome. In: Hoffman R, Benz EJ Jr, Shattil SJ, et al, eds. Hoffman Hematology: Basic Principles and Practice. 5th ed. Philadelphia, Pa: Churchill Livingstone Elsevier;2008:chap 139.
Schafer A. Hemorrhagic disorders: Abnormalities of platelet and vascular function. In: Goldman L, Ausiello D, eds. Cecil Medicine. 23rd ed. Philadelphia, Pa:Saunders Elsevier;2007:chap 179.
Reviewed ByReview Date: 02/28/2011
David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine; and Yi-Bin Chen, MD, Leukemia/Bone Marrow Transplant Program, Massachusetts General Hospital. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.
Thrombotic Thrombocytopenic Purpura (TTP). It's a rare blood disorder that effects your platlets and organs
If you aren't in danger of going unconscious while driving then you should be able to drive.
Thrombotic thrombocytopenic purpura (TTP)
It is Thrombotic Thrombocytopenic Purpura. In this process, blood clots (or thromboses) form in small blood vessels, leading to low platelet counts (thrombocytopenia) in the blood, along with skin manifestations (purpura).
Thrombotic thrombocytopenic purpura (TTP) is a rare blood disorder characterized by excessive clotting throughout the body's small blood vessels. This clotting can lead to a decrease in platelet count, causing anemia and symptoms like bruising, bleeding, and organ damage. TTP is considered a medical emergency and requires prompt treatment to prevent complications.
a rare blood disorder
Thrombocytopenic Purpura
idiopathic thrombocytopenic purpura
because your not supposed to inject it. If you injected the new formulation, go to the hospital immediately and tell them what you did. Shooting the new opana can cause thrombotic thrombocytopenic purpura, which is deadly in 90%+ cases that arent treated
It is a disorder in which the immune system targets and destroys blood platelets
its when you have a low platelet count and become at risk of bruising or bleeding. they dont know what causes it. it can go away fast or it can become chronic. its more common among infants and elders than teens and young adults. its no fun. :(
Acute ITP is characterized by bleeding into the skin or from the nose, mouth, digestive tract, or urinary tract. The onset is usually sudden. Bleeding into the skin takes the form of purpura or petechiae. Purpura is a purplish or reddish-brown.