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What would be the likely outcome if a microbe could prevent the activation of C3 in the complement cascade?

If a microbe can prevent the activation of C3 in the complement cascade, it would likely evade the host immune response and avoid being targeted for destruction. This evasion strategy could help the microbe establish infection and cause disease without being effectively eliminated by the immune system.


What 3 ways of complement cascade is helpful in fighting infection?

Lysis


Why IGM is so much efficient in activating complement than IgG?

IgM is more efficient in activating complement than IgG because of its larger size and pentameric structure, which allows for more binding sites and better clustering of complement proteins. This leads to a more robust activation of the complement cascade and increased inflammation and opsonization.


What is the function of the complement cascade called opsonization?

Opsonization is a process in which pathogens are marked for destruction by phagocytic cells. It involves the binding of complement proteins to the surface of the pathogen, making it easier for phagocytes to recognize and engulf the pathogen.


What immunoglobulin is the most common in blood and initiates the complement cascade?

Both IgG and IgM initiates complement. IgG is far more abundant in the body however this does not necessarily means that it initiates complement more. IgM is the 1st immunoglobulin that responds to a foreign antigen as part of the body's hormonal response. So to answer the question directly, neither immunoglobulin initiate the complement cascade more than the other. Some research seems to indicated that there is no significant difference in ability to bind complement between IgG and IgM via the classical pathway in humans.


In addition to IgC the antibodies that can fix complement are?

IgG and IgM can fix complement by activating the C3 protein at the end of the complement cascade allowing ADCC (antibody dependent cell- mediated cytoxicity) to occur. I have never heard of an IgC antibody. In humans there are only 5 classes of antibodies: IgM, IgG, IgA. IgD & IgE.


What is complement activation?

Complement activation is a cascade of proteins in the immune system that helps to opsonize pathogens for phagocytosis, recruit inflammatory cells, and directly lyse target cells. It can be activated through three pathways: classical, lectin, and alternative pathways, and plays a critical role in innate immunity.


What plasma proteins are complement proteins?

Complement proteins are a series of immune proteins that carry out complement cascade reactions. These proteins are helping the immune system to lean up from the cells. complement proteins are not antibodies.


What does the term event mean in math?

An event is an outcome or set of outcomes of an experiment. For example, if you want a coin to land on heads when you are flipping it, and it DOES land on heads, THAT is the event. If it lands on tails, that outcome is the complement


Which has higher elevation cascade range or Ozark plateau?

The Cascade Range


Where is the Cascade Public in Cascade located?

The address of the Cascade Public is: 105 N Front St, Cascade, 83611 0010


Where is the Cascade Public Library in Cascade located?

The address of the Cascade Public Library is: 301 1St Av W, Cascade, 52033 0117