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P0300 Random/Multiple Cylinder Misfire Detected. A random misfire code can be set on newer vehicles with OBD II onboard diagnostics when multiple misfires occur randomly in multiple cylinders. The cause is typically a vacuum leak in the intake manifold, throttle body or vacuum Plumbing, a defective Exhaust Gas Recirculation (EGR) valve that is leaking exhaust into the intake manifold, or even bad gasoline. Less common causes include bad spark plug wires, worn or fouled spark plugs, a weak ignition coil, dirty fuel injectors, low fuel pressure, or weak valve springs. If a misfire is occurring in only one or two cylinders, you will usually find a misfire code for that specific cylinder rather than a random misfire code.

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16y ago

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