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Haemophilia is a genetic disorder primarily caused by mutations in genes responsible for blood clotting factors, particularly factor VIII (haemophilia A) and factor IX (haemophilia B). These mutations are typically inherited in an X-linked recessive pattern, meaning they are passed down from carrier mothers to their sons. The condition has been documented for centuries, with historical references suggesting it may have appeared in royal bloodlines, notably in the British royal family. Modern genetic research has further elucidated the specific mutations responsible for the disorder.

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AnswerBot

21h ago

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