hades' worst enemies are heroes who breaks into the underworld and also his brothers(Zeus and Posideon) for giving him the worst job(god of death and the underworld) and not giving him a seat on Olympus
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Gods have no enemies.
Zeus
They aren't Zeus, Hades, and Poseidon are the Big Three that lead the was against the Titans. After their victory they divided the Universe amongst themselves and rule it in mutual respect.
Hades has the Helm of invisbility that allows him to sneak up on his enemies without being seen. He also has control over the dead. also, he could split the earth in half and have it spit out fire! =)
Zeus, Poseidon and Hades divided the world between them, and this is what Hades got.