No, they are not; Apollo is a son of Zeus, who is brother of Hades.
Both gods further something to do with death; Apollo who strikes down men and boys with his arrows, and Hades who rules the dead.
Persephone enemy was Methane because she slept with Persephone's husband, Hades.
Hades is the god of the Underworld and Apollo's uncle. Apollo is the god of prophecy and oracles, healing, plague and disease, music, song and poetry, archery, and the protection of the young. Apollo's son Asklepios, when mortal, was killed at Hades request by Zeus because he healed the dead to bring them back to life thus disturbing the natural balance that Hades maintained between living and dead. However, Apollo is not known to encounter Hades in Greek myth.
Gods have no enemies.
Zeus, I think.
Gods have no enemies.
Zeus
apollo
hades the god of the underworld
Hermes
No that irksome duty is the responsibility of Hades.
Zeus is the father of Hercules, and Hades is the elder brother of Zeus. In short, Hades was the uncle of Hercules.
hades' worst enemies are heroes who breaks into the underworld and also his brothers(Zeus and Posideon) for giving him the worst job(god of death and the underworld) and not giving him a seat on Olympus