When a macrophage engulfs a foreign antigen, it phagocytizes it (or breaks it down) using enzymes. The fragments (called epitopes) of the original antigen are transported to the cell surface so that helper T-cells that specifically match the antigen can recognize it. When that happens, the helper-T cells are able to trigger a specific immune response to that exact antigen by stimulating more helper-T cells to be produced and by triggering B-cells to secrete antigen-specific antibodies that mark infected cells for destruction by killer T-cells.
Antigens are displayed on the surface of a macrophage after the digestion of a bacterium.
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Macrophages ( in the lymph nodes ) act like phagocytes to engulf and digest the pathogen. But they do not fully digest it. They separate out the antigens and incorporate them into a cell surface molecule. This is exposed on the surface of the macrophage, which becomes known as an antigen-presenting cell. Its function is to find the lymphocytes that can neutralise that particular antigen.
presents antigens of an engulfed pathogen in its class II MHC molecules to helper T cells, and releases IL-1
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The structure on the macrophage that activates T cells is the Major Histocompatibility Complex (MHC) molecule, specifically MHC class II. Macrophages present processed antigens on these MHC class II molecules to CD4+ T helper cells, initiating T cell activation. This interaction is crucial for the adaptive immune response, as it helps T cells recognize and respond to specific pathogens. Additionally, co-stimulatory signals from other surface proteins on the macrophage are necessary for full T cell activation.
Blood antigens A and B are located on the surface of red blood cells, while the Rh antigen (Rh factor) is also found on the surface of red blood cells. These antigens determine an individual's blood type.
All cells produce antigens, or cell surface markers. The only question is whether the antigens are self antigens which means they belong in the body or they're foreign antigens which means they are an invading bacteria or virus (or a cancerous cell).
The ABO blood group antigens are located on the surface of red blood cells. These antigens determine an individual's blood type (A, B, AB, or O) and are inherited from their parents. The presence or absence of A and B antigens determines a person's blood type.
Antigens, by definition, cause the body to produce antibodies which act against them. You inherit certain antigens which are on your red blood cells. Sometimes these antigens are absent from your RBC. If you are type B, you have B antigens. Type A has A antigens, AB has AB antigens and type O has no antigens. If you are type AB, you can receive AB blood from some one else.
Blood type AB has both A and B antigens.
Yes, AB blood has both A and B antigens present on the surface of red blood cells.