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ACE inhibitors block angiotensin, a natural vasoconstrictor, this in turn allows blood vessels to relax and thereby reduce the blood pressure. When blood pressure is reduced in heart failure this helps to lower the workload of the failing heart. In other words, the failing heart does not have to pump against a high pressure (imagine taking a water hose and clamping it, very little water comes through the end and you can feel the pressure building up- this is what happens when blood pressure is high and a failing heart's left ventricle has to pump the blood out to the body).

This is how I explain it to my students. Hope this helps

A RN educator in NJ

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14y ago

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