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Osteoarthritis, degenerative joint disease that leads to degeneration of protective joint cartilages.Osteoarthritis is most common type of Arthritis majorly affecting geriatric female population globally. Generally the disease remains asymptomatic at beginning, which at later stages is characterized by joint pain and loss of motor function. The interplay of risk factors including mechanical stress, abnormal joint mechanics, obesity, etc. are major causes of osteoarthritis. During early stage surface fibrillation, and focal erosion occurs which extends further. At microscopic level the collagen matrix is damaged followed by cartilage injury.

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