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MVO2 represents the volume of oxygen consumed by the heart and therefore is not inversely proportional to heart rate but directly proportional. The greater the heart rate the greater work (stress) put on the heart and thus an increase in myocardial oxygen demand. An approximated equation for MVO2 is: MVO2~HR*Systolic blood pressure. Coronary artery flow on the the other hand is inversely related to HR because coronary flow takes place during diastole and because an increase in heart rate decrease diastolic time coronary flow is reduced.

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