0
Why did your Systemic Lupus Erythematosus lead to a heart attack?
Wiki User
∙ 14y ago
People with systemic lupus erythematosus have double the risk of cardiovascular events. There are several reasons. Lupus is inflammatory. The inflammation affects the blood vessels ultimately reducing elasticity and increasing the likelihood of atherosclerosis (hardening of the arteries). Prednisone, used to treat lupus, also increases the change of atherosclerosis. Some lupus patients experience inflammation of the heart (pericarditis, endocarditis, myocarditis). The pain and fatigue that accompany lupus make those with the disease less likely to exercise thereby increasing the risk of heart attack and stroke. The sedentary lifestyle and some of the medcations predispose the lupus patient to obesity, another risk factor in cardiovascular events. The stress and depression that accompany living with an unpredictable chronic condition increase the risk even more. Lupus patients may also have some of the clotting factors (anticardiolipin, lupus anticoagulant, antiphospholipid antibodies) that cause blood clots. Lupus may result anemia, or irregular sizes in red blood cells affecting the amount of oxygen that gets to the heart muscle.
Wiki User
∙ 14y ago
Add your answer:
Earn +20 pts
What is the systemic heart chamber?
The left ventricle pumps blood to the systemic loop.
The left side of the heart performs the?
systemic circulation .
Is human heart represents systemic circulation?
yes.
Does systemic circulation supply nutrients and oxygen to the heart?
no
What is the flow of blood to the tissues of the heart?
coronary circulation
What is a Chronic inflammatory disease affecting skin kidneys heart and lungs?
Systemic Lupus Erythematosus (SLE)
What body systems may be affected by Systemic lupus erythematosus?
Targets may include the brain, kidneys, heart, pancreas, or other organs
What do laboratory results indicate about the causes of pericarditis?
Bacteria (staphylococcus aureus) is a sign of bacterial pericarditis. Excessive protein indicates systemic lupus erythematosus or heart attack. An elevated white blood cell count may indicate fungal infection.
What is another name for lupus?
There are 3 main types of lupus (that i know of): '''Drug-Induced lupus''' (lasting only for the duration of the medication causing it) '''Discoid lupus''' (effecting mainly the skin and extremities) '''Systemic lupus erythematosus''' (effecting almost everything; kidneys, brain, heart, lungs, skin, joints, muscles)
What complications can occur with systemic lupus?
most systemic lupus patients eventually die from infections or from heart disease complicated by long-term use of corticosteroids
Systemic lupus erythematosus sounds quite nasty but what is it?
Systemic lupus erythematosus (SLE or lupus) is a chronic autoimmune disease that is potentially debilitating and sometimes fatal as the immune system attacks the body's cells and tissue, resulting in inflammation and tissue damage. SLE can affect any part of the body, but most often harms the heart, joints, skin, lungs, blood vessels, liver, kidneys and nervous system. The course of the disease is unpredictable, with periods of illness (called flares) alternating with remission. Lupus can occur at any age, and is most common in women, particularly of non-European descent. Lupus is treatable symptomatically, mainly with corticosteroids and immunosuppressants, though there is currently no cure.== == The word itself is also Latin for Wolf
What happens to the inside of the body when a person has lupus?
Systemic lupus erythematosus affects each patient differently. Lupus is always marked by inflammation which is the result of autoimmune activity. The majority of people with lupus have joint and muscle pain along with profound fatigue. Half of them have lupus kidney disease. The chronic inflammation greatly increases the risk of cardiovascular disease. The three leading causes of death in lupus are uncontrolled infection, kidney failure and heart attacks/strokes. Lupus can affect any other organ in the body.
Which percentage of lupus cases are SLE Systemic Lupus Erythmatosus?
Systemic lupus accounts for approximately 70 percent of all cases of lupus. In approximately half of these cases, a major organ, such as the heart, lungs, kidneys or brain, will be affected. Cutaneous lupus (affecting only the skin) accounts for approximately 10 percent of all lupus cases. Drug-induced lupus accounts for about 10 percent of all lupus cases and is caused by high doses of certain medications. The symptoms of drug-induced lupus are similar to systemic lupus; however, symptoms usually subside when the medications are discontinued.
Does Toni Braxton have Lupus?
Toni Braxton was diagnosed in 2008 when she was hospitalized with what doctors thought was a heart attack. On further in vestigation, the doctors diagnosed her with lupus. Lupus can affect any of the muscle layers of the heart. Lupus patients are 50 times more likely to suffer a heart attack than the general population.
What system affect the lupus erythematosus?
Lupus can affect virtually every body system. For some people, there is no organ involvement. 50% of people with lupus will have kidney disease. Lupus frequently affects the heart and lungs. Pericarditis and pleurisy are common. Lupus can affect the central nervous system causing seizures, headaches, and cognitive impairment. Involvement of other body systems is less common but does occur. Lupus frequently occurs in overlap with other autoimmune conditions. In those cases, it is difficult to determine which disease is causing which damage.
What organs are involved in kidney disease?
Lupus can affect the brain, heart, skin, kidneys, liver, lymph nodes, stomach and really any organ in the human body. Approximately 40% of people wth systemic lupus erythematosus will develop lupus nephritis (kidney disease).
Drug-induced lupus erythematosus?
DefinitionDrug-induced lupus erythematosus is an autoimmune disorder that is brought on by a reaction to medication.See also: Systemic lupus erythematosus (SLE)Causes, incidence, and risk factorsDrug-induced lupus erythematosus is similar to systemic lupus erythematosus (SLE). It is caused by a hypersensitivity reactionto a medication. The drug may react with cell materials, causing the body to form antibodies that attack the body's own healthy cells.Several medications are known to cause drug-induced lupus. They include:ChlorpromazineHydralazineIsoniazidMethyldopaPenicillamineProcainamideQuinidineSulfasalazineSymptoms tend to occur after taking the drug for at least 3 to 6 months.Persons with drug-induced lupus erythematosus may have symptoms that affect the joints (arthritis), heart, and lungs. Other symptoms associated with SLE, such as lupus nephritis and nervous system (neurological) disease, are rare.Drug-induced lupus affects men and women equally.SymptomsBlurred visionFeverGeneral ill feeling (malaise)Joint painJoint swellingLoss of appetitePleuritic chest painSkin rashGets worse with sunlight"Butterfly" rash across bridge of nose and cheeksWeight lossSigns and testsThe health care provider will listen to your chest with a stethoscope. The doctor may hear a sound called a heart friction rub or pleural friction rub. There may be signs of pericarditis.A skin exam shows a rash.Tests that may be done include:Antihistone antibodyAntinuclear antibody (ANA) panelLupus erythematosus cell test (rarely used)A chest x-raymay show signs of pleuritis or pericarditis. An ECG may show that the heart is affected.TreatmentUsually, symptoms go away within several days to weeks after stopping the medication that caused the condition.Treatment may include:Nonsteroidal anti-inflammatory drugs (NSAIDs) to treat arthritis and pleurisyCorticosteroid creams to treat skin rashesAntimalarial drugs (hydroxychloroquine) to treat skin and arthritis symptomsVery rarely, high doses of corticosteroids (prednisone, methylprednisolone) and immune system suppressants (azathioprine or cyclophosphamide) are used to treat persons with severe drug-induced lupus that affects the heart, kidney, and neurological system.Protective clothing, sunglasses, and sunscreen are recommended.Expectations (prognosis)Drug-induced lupus erythematosus is usually not as severe as SLE. Usually, the symptoms go away within a few days to weeks after stopping the medication.You should avoid the medication in the future, or symptoms usually return. Routine eye exams are recommended to detect eye complications early.ComplicationsInfectionThrombocytopenia purpura -- bleeding near the skin surface, resulting from a low number of platelets in the bloodHemolytic anemiaMyocarditisPericarditisCalling your health care providerCall for an appointment with your health care provider if:Your symptoms do not improve after you stop taking the medication that caused the conditionYou develop new symptomsPreventionBe aware of the risk when taking medications that are known to cause this reaction. If symptoms begin to appear, contact your doctor.ReferencesTassiulas IO, Boumpas DT. Clinical features and treatment of systemic lupus erythematosus. In: Firestein GS, Budd RC, Harris Jr. ED, McInnes IB, Russy S, Sergent JS, eds. Kelley's Textbook of Rheumatology. 8th ed. St. Louis, Mo: WB Saunders; 2008: chap 75.
