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People with systemic lupus erythematosus have double the risk of cardiovascular events. There are several reasons. Lupus is inflammatory. The inflammation affects the blood vessels ultimately reducing elasticity and increasing the likelihood of atherosclerosis (hardening of the arteries). Prednisone, used to treat lupus, also increases the change of atherosclerosis. Some lupus patients experience inflammation of the heart (pericarditis, endocarditis, myocarditis). The pain and fatigue that accompany lupus make those with the disease less likely to exercise thereby increasing the risk of heart attack and stroke. The sedentary lifestyle and some of the medcations predispose the lupus patient to obesity, another risk factor in cardiovascular events. The stress and depression that accompany living with an unpredictable chronic condition increase the risk even more. Lupus patients may also have some of the clotting factors (anticardiolipin, lupus anticoagulant, antiphospholipid antibodies) that cause blood clots. Lupus may result anemia, or irregular sizes in red blood cells affecting the amount of oxygen that gets to the heart muscle.

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What is a Chronic inflammatory disease affecting skin kidneys heart and lungs?

Systemic Lupus Erythematosus (SLE)


What body systems may be affected by Systemic lupus erythematosus?

Targets may include the brain, kidneys, heart, pancreas, or other organs


What is another name for lupus?

There are 3 main types of lupus (that i know of): '''Drug-Induced lupus''' (lasting only for the duration of the medication causing it) '''Discoid lupus''' (effecting mainly the skin and extremities) '''Systemic lupus erythematosus''' (effecting almost everything; kidneys, brain, heart, lungs, skin, joints, muscles)


What complications can occur with systemic lupus?

most systemic lupus patients eventually die from infections or from heart disease complicated by long-term use of corticosteroids


What is the worst type of Lupus?

The worst type of lupus is often considered to be systemic lupus erythematosus (SLE). SLE can affect multiple organ systems, including the kidneys, heart, and brain, leading to severe complications. Its unpredictable flare-ups and potential for serious damage make it particularly challenging to manage. Other forms of lupus, such as cutaneous lupus or drug-induced lupus, are generally less severe and primarily affect the skin or are triggered by medications.


Systemic lupus erythematosus sounds quite nasty but what is it?

Systemic lupus erythematosus (SLE or lupus) is a chronic autoimmune disease that is potentially debilitating and sometimes fatal as the immune system attacks the body's cells and tissue, resulting in inflammation and tissue damage. SLE can affect any part of the body, but most often harms the heart, joints, skin, lungs, blood vessels, liver, kidneys and nervous system. The course of the disease is unpredictable, with periods of illness (called flares) alternating with remission. Lupus can occur at any age, and is most common in women, particularly of non-European descent. Lupus is treatable symptomatically, mainly with corticosteroids and immunosuppressants, though there is currently no cure.== == The word itself is also Latin for Wolf


What happens to the inside of the body when a person has lupus?

Systemic lupus erythematosus affects each patient differently. Lupus is always marked by inflammation which is the result of autoimmune activity. The majority of people with lupus have joint and muscle pain along with profound fatigue. Half of them have lupus kidney disease. The chronic inflammation greatly increases the risk of cardiovascular disease. The three leading causes of death in lupus are uncontrolled infection, kidney failure and heart attacks/strokes. Lupus can affect any other organ in the body.


Does Toni Braxton have Lupus?

Toni Braxton was diagnosed in 2008 when she was hospitalized with what doctors thought was a heart attack. On further in vestigation, the doctors diagnosed her with lupus. Lupus can affect any of the muscle layers of the heart. Lupus patients are 50 times more likely to suffer a heart attack than the general population.


Which percentage of lupus cases are SLE Systemic Lupus Erythmatosus?

Systemic lupus accounts for approximately 70 percent of all cases of lupus. In approximately half of these cases, a major organ, such as the heart, lungs, kidneys or brain, will be affected. Cutaneous lupus (affecting only the skin) accounts for approximately 10 percent of all lupus cases. Drug-induced lupus accounts for about 10 percent of all lupus cases and is caused by high doses of certain medications. The symptoms of drug-induced lupus are similar to systemic lupus; however, symptoms usually subside when the medications are discontinued.


What are the functional limitations of a person with SLE?

Functional limitations of a person with systemic lupus erythematosus (SLE) can vary widely depending on the severity of their symptoms. Common limitations may include fatigue, joint pain, muscle weakness, and impaired mobility. SLE can also affect organs such as the kidneys, heart, and lungs, leading to additional functional limitations.


What system affect the lupus erythematosus?

Lupus can affect virtually every body system. For some people, there is no organ involvement. 50% of people with lupus will have kidney disease. Lupus frequently affects the heart and lungs. Pericarditis and pleurisy are common. Lupus can affect the central nervous system causing seizures, headaches, and cognitive impairment. Involvement of other body systems is less common but does occur. Lupus frequently occurs in overlap with other autoimmune conditions. In those cases, it is difficult to determine which disease is causing which damage.


What are the differences between Scarcoidosis and Lupus?

Sarcoidosis and lupus are both inflammatory diseases, but they have distinct characteristics. Sarcoidosis primarily involves the formation of granulomas—small clusters of inflammatory cells—often affecting the lungs, lymph nodes, and skin, and its cause is often unknown. In contrast, lupus (systemic lupus erythematosus) is an autoimmune disease that can affect multiple organ systems, including the skin, joints, kidneys, and heart, and is characterized by a variety of symptoms such as fatigue, joint pain, and a distinctive butterfly-shaped rash. Diagnosis and treatment approaches also differ significantly between the two conditions.