Florence became a major city during the renaissance because the Medici family, who was very rich and powerful at the time, sponsored many artists and without them they wouldn't have been able to create and sell so much work.
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Michelangelo, Donatello, and the DeMedicisall helped to make Florence the cultural center of renaissance Europe.
Florence.
Italy
It was the center of the Reformation, which started the Renaissance period.
Renaissance Center was created in 1977.