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To drain the coolant from a 2002 Lexus RX 300, first ensure the engine is cool and then locate the radiator drain plug at the bottom of the radiator. Place a drain pan underneath the radiator, open the drain plug, and allow the coolant to flow out completely. Additionally, you may want to remove the radiator cap to facilitate draining. Once drained, close the drain plug securely before refilling with new coolant.

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