answersLogoWhite

0

The driving distance between Des Moines, IA and Chicago, IL is approximately 335 miles. The driving time would be approximately 5 hours if you were to travel non-stop in good driving conditions. (The driving time does not take into consideration conditions which may extend trip time such as weather, road work, border crossings and rush hour traffic in urban areas.)

User Avatar

Wiki User

7y ago

What else can I help you with?