It is 603 miles according to Google Maps.
via I-40, its 387 miles
It is 503 miles (8 hours 34 minutes) from Chicago, Illinois to Murfreesboro, Tennessee if you travel via I-65 South.
508 miles
70 miles taking this route:Take U.S. 11E SOUTH, from Greeneville, to I-81 SOUTH to KNOXVILLE.Take I-81 SOUTH to I-40 WEST to KNOXVILLE at EXIT 0B.Take I-40 WEST to KNOXVILLE.
It is 304 miles according to Google Maps.
It is 322 miles according to Google Maps.
The driving distance is 257 miles per Map Quest. The driving time is 4 hours and 6 minutes.
35 mls
The driving distance from Knoxville, Tennessee to Nashville, Tennessee is 180 miles via I-40 W per MapQuest. The driving time per MapQuest is 2 hours and 45 minutes.
There are two different Brentwoods in Tennessee. One is only 11 miles and the other near Knoxville is 172 miles from Nashville.
If you follow the roads I-40 W and I-24 W it is roughly 480 miles from Knoxville, Tennessee to St. Louis, Missouri.