How far is it from Venice FL to Hilton Head SC?

Answer 1

480 miles taking this route:

1. Take I-75 NORTH from Venice to I-10 to JACKSONVILLE and TALLAHASSEE at EXIT 435. Follow signs to I-10 EAST to JACKSONVILLE.
2. Take I-10 EAST to I-95 NORTH to SAVANNAH via I-295 NORTH to bypass Jacksonville. (EXIT 356 off I-10 to get onto I-295. Follow signs to I-295 NORTH to INT'L AIRPORT and SAVANNAH; then take EXIT 35B off I-295 to get onto I-95 NORTH towards INT'L AIRPORT and SAVANNAH.)
3. Take I-95 NORTH to U.S. 278 to BEAUFORT and HILTON HEAD IS. at EXIT 8 in South Carolina north of Savannah.
4. Turn right off the exit ramp onto U.S. 278 EAST. Take U.S. 278 EAST to Hilton Head Island.