How long does it take to drive from Cairo to Cape Town?

Answer 1

It would take you about 88 and a half hours, or about 3 and a half days.

UPDATE

Realistically, given multiple border crossings and other bureaucracy, it will be more like several weeks. The hard part is Sudan and Southern Sudan. Egypt has good to medium roads. Southern Sudan does not.

You have to travel on a ferry along the Nile for a while as well, as there are no roads parallel to the Nile, which is very slow.

Once through Sudan and Southern Sudan, you can drive through Kenya, Tanzania, Malawi, Zambia, Botswana or Zimbabwe and then South Africa through to Cape Town. The main roads are mostly tarred from Kenya onwards though not necessarily in good condition.

In South Africa much of the drive is double lane highways in good condition.

If you like beaches come through Kenya, Tanzania, Mozambique, South Africa along the east coast. Its very pretty, but slower and you need a good 4x4 vehicle. Toyota is best as spares are available anywhere.