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267 miles taking this route:

  1. Take PA-72 NORTH from Lancaster to I-81 north of Lebanon. Follow signs to I-81, then follow signs to I-81 NORTH.
  2. Take I-81 NORTH to I-90 New York State THRUWAY (toll) to ALBANY and BUFFALO at EXIT 25A in Syracuse. Follow signs to I-90 WEST to BUFFALO.
  3. Take I-90 WEST on the THRUWAY to Liverpool. Liverpool is the first couple of exits.
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