It is around 310 miles.
The route:
163 miles
117 miles
There are 202 miles between Naples, FL & Orlando, FL, according to travelmath.com.
255 miles
That would be 87.8 miles.
42.77 miles
123 miles
The distance from Gainesville, FL to Naples, FL is approximately 270 miles if driving via I-75 South.
The driving distance between Naples, FL and Daytona, FL is approximately 245 miles. The driving time would be approximately 4 hours 45 minutes if you were to travel non-stop in good driving conditions. (The driving time does not take into consideration conditions which may extend trip time such as weather, road work and rush hour traffic in urban areas.)
The distance from Spring Hill, FL to Naples, FL is approximately 177 miles via I-75 S.
127.61 Miles
It is 202.47 miles according to MapQuest.