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275 miles taking this route:

  1. Take PA-309 NORTH from Tamaqua to PA-54 in Hometown. Turn left onto PA-54 WEST.
  2. Take PA-54 WEST to I-81. At JCT I-81, follow signs to I-81 SOUTH to HARRISBURG.
  3. Take I-81 SOUTH to I-76 Pennsylvania TURNPIKE off EXIT 52 in MIDDLESEX (near Carlisle).
  4. Turn right off the exit ramp, then follow signs to the PENNSYLVANIA TURNPIKE. Once you are past the toll booth, follow signs to I-76 WEST to PITTSBURGH.
  5. Take I-76 WEST on the PENNSYLVANIA TURNPIKE (toll road) to Pittsburgh. To get to the city itself, take I-376 WEST (EXIT 57 off the PENNSYLVANIA TURNPIKE).
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14y ago

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