Interstate 80 connects the two. If you drive across the George Washington Bridge, you won't have to make any turns.
route 66
Take I-95 SOUTH to Washington, D.C.
use the 5
Take the Coastal Highway (SR-1) NORTH to San Francisco.
E842 is the best route across. SS16 to A14 connects to that.
Interstate - 5.
The best route to drive from Chicago to Pittsburgh is to take Interstate 90 East to Interstate 80 East. This route is the most direct and efficient way to reach Pittsburgh from Chicago by car.
It depends on traffic and what route you take, that's all that can be really said. The best average would be about 1.5 hours to cover that 71 miles.
Personally I'd probably use the I-80 route.
a popular cattle drive route in the years after the Civil War
The quickest and shortest route is I-5 North.
The best route for a drive from Salt Lake City to Denver is typically via Interstate 80 East and Interstate 25 South. This route is the most direct and commonly used for traveling between the two cities.