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spleen is a secondary lymphoid organ. let me explain this in simple word. spleen has abundant macrophages, which can sense abnormalities of red blood cells(RBC) and pletlet. abnormal and old RBC and pletlet are removed from circulation by spleen. so many conditions in which spleen gets bigger that would remove more pletlet even if they are normal, leading to decrese the count of pletlet.

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16y ago

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