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  • The pituitary gland, or hypophysis, is found at the base of the brain below the hypothalamus and the two structures are connected via the infundibulum, or pituitary stalk, which carries both axons and blood vessels.

  • The pituitary gland is about 1- 1.5 cm in diameter and weighs approximately 0.5g although it tends to weigh approximately 20% more in women and may increase by 10% during pregnancy. It sits in the sella turcica which is a depression of the sphenoid bone at the base of the skull and lies behind the sphenoid sinus.

  • The top of the sella turcica is covered by a diaphragm, which has a foramen in the centre through which the infundibulum passes.

  • Superior to the diaphragm is the optic chiasm.

  • The pituitary gland can be divided into two functionally and embryologically distinct parts. These are the anterior pituitary, or adenohypophysis, and the posterior pituitary, or neurohypophysis.

  • The anterior pituitary makes up 75% of the total weight of the pituitary. The pars distalis forms the major part of the gland. The pars intermedia is rudimentary in man. The pars tuberalis runs up the pituitary stalk.

  • The posterior pituitary is made up of neuronal processes and glia as an extension of the hypothalamus and its major part is the pars distalis, which lies behind the anterior pituiary in the sella turcica.

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14y ago

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