Yes they do, in about 3-4 months. They have no nucleus so they cannot reproduce. They loose their nucleus so they have room for hemoglobin molecules. They usually die in the spleen and get broken down in the liver. This is where they are turned into bilirubin. Some of the bilirubin is used to make bile, the rest is excreted in your feces, that is what gives it the brownish color.
Saponin is a type of toxic glycoside that forms a frothy colloidal solution on shaking with water. It breaks down red blood cells by dissolving the membranes of the cells.
You can be diabetic or the break down of red blood cells
Hemolytic is when red blood cells are broken down inside the body. The spleen is generally an organ that does this in the human body. Its function is to break down the red blood cells and making hemoglobin.
Break down red blood cells Make antibodies
Damaged red blood cells are filtered by the spleen where they're broken down. Red blood cells are formed in the bone marrow.
Liver, the red blood cells are broken down into bile.
Packed, spun-down or lysed red blood cells would be better.
Sickle cells have an abnormality in the oxygen-carrying protein hemoglobin. Functionally, sickle cells are more rigid than normal red-blood cells. This can result in them getting "stuck" in capillaries because they don't deform as well as normal red-blood cells to allow them to flow through the capillaries. The sickle cells also break down faster than normal red-blood cells - due to their decreased elasticity they are more prone to "break" when trying to deform to flow through the blood vessels and capliaries, leading to anemia.
It is a major contributor of white blood cells, red blood cells and platelets. It also has cells in the bone itself that make and break down bone called osteoblasts and osteoclasts.