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Age and damaged (senescent) red blood cells (erythrocytes) are broken down and recycled by the spleen, although the liver also plays an important role.

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When erythrocytes are broken down the heme group is excreted as what?

iron


How are aged and damaged erythrocytes removed from circulation?

Aged and damaged erythrocytes are primarily removed from circulation by the spleen, where specialized macrophages recognize and phagocytize these defective cells. The liver also plays a role in this process, filtering blood and removing senescent red blood cells. In addition, the reticuloendothelial system contributes by breaking down hemoglobin from these cells, recycling iron and producing bilirubin as a byproduct. This ensures the maintenance of healthy red blood cell populations and proper metabolic functions.


What is the fate of aged or damaged red blood cells?

After about 90 to 120 days they get brittle and are filtered from the blood (mainly) by the liver and the spleen. Most of the chemicals are released into the blood where they are taken up by the bone marrow and used in the production of new red blood cells. But a fair amount of hemoglobin is broken down by the liver and is added to the bile - where its only function is to color your solid waste.


Where are worn-out or damaged red blood cells broken down?

lysomes ! =]


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Where from hemoglobin formed in human body?

Hemoglobin is produced in bone marrow by erythrocytes and is circulated with them until their destruction. It is then broken down in the spleen, and some of its components, such as iron, are recycled to the bone marrow. Other components, such as the heme groups, are broken down into bilirubin, transported to the liver, and secreted with the bile into the intestine for eventual elimination from the body.


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What removes aged and defective red blood cells?

The spleen is responsible for removing aged and defective red blood cells from circulation. These old cells are broken down by macrophages within the spleen and recycled for the production of new red blood cells.


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