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DNA methylation in prokaryotes?
In prokaryotes, DNA methylation is a common epigenetic modification that involves the addition of a methyl group to cytosine bases in DNA. This process plays a role in regulating gene expression, DNA replication, and protection against foreign DNA such as viruses. DNA methylation patterns can vary between species and are important for controlling various cellular processes.
How does DNA methylation regulate gene activity?
DNA methylation is a process where methyl groups are added to specific regions of DNA, which can turn genes on or off. This modification can affect how genes are read and expressed, ultimately regulating gene activity.
What does Methylation of DNA prevent?
Methylation of DNA can regulate gene expression by preventing transcription factors from binding to specific regions of DNA, thereby silencing gene expression. Additionally, methylation of DNA can help stabilize the structure of chromosomes and maintain genomic stability.
What is the relationship between methylation and genomic imprinting?
Methylation is a process where methyl groups are added to DNA, which can affect gene expression. Genomic imprinting is a phenomenon where certain genes are expressed based on whether they are inherited from the mother or father. Methylation plays a key role in genomic imprinting by regulating which parent's gene is expressed.
How does DNA ligase utilize ATP during the process of DNA repair and replication?
DNA ligase utilizes ATP during the process of DNA repair and replication by using the energy from ATP to catalyze the formation of a phosphodiester bond between the DNA strands, sealing any breaks or gaps in the DNA molecule.
DNA methylation in prokaryotes?
In prokaryotes, DNA methylation is a common epigenetic modification that involves the addition of a methyl group to cytosine bases in DNA. This process plays a role in regulating gene expression, DNA replication, and protection against foreign DNA such as viruses. DNA methylation patterns can vary between species and are important for controlling various cellular processes.
How does DNA methylation regulate gene activity?
DNA methylation is a process where methyl groups are added to specific regions of DNA, which can turn genes on or off. This modification can affect how genes are read and expressed, ultimately regulating gene activity.
What does Methylation of DNA prevent?
Methylation of DNA can regulate gene expression by preventing transcription factors from binding to specific regions of DNA, thereby silencing gene expression. Additionally, methylation of DNA can help stabilize the structure of chromosomes and maintain genomic stability.
What protect the DNA?
Methylation protects DNA from nucleases, endonucleases
What is the chemical basis of gene imprinting?
Gene imprinting involves the addition of methyl groups to specific regions of DNA, a process known as DNA methylation. This methylation pattern is established during early development and can result in certain genes being silenced based on whether they were inherited from the mother or the father. It plays a critical role in regulating gene expression and cellular differentiation.
How does doxorubicin affect DNA methylation?
Doxorubicin can induce changes in DNA methylation patterns by affecting the activity of DNA methyltransferase enzymes. It can lead to global hypomethylation or hypermethylation of specific gene promoters, influencing gene expression and potentially contributing to its cytotoxic effects.
Where does methelation bind?
Methylation typically occurs on nitrogen or oxygen atoms in biological molecules such as proteins, DNA, and RNA. For example, in DNA, methylation often occurs on cytosine bases. Methylation can also occur on histone proteins associated with DNA to regulate gene expression.
Will methylation of DNA tend to turn a gene on or off?
off
What has the author Xiaolin Zhang written?
Xiaolin Zhang has written: 'Mutagenic mechanisms associated with DNA cytosine methylation, DNA base sequence context and DNA precursor pool asymmetry' -- subject(s): Mutagenesis, DNA, Nucleotide sequence, Methylation
What is the relationship between methylation and genomic imprinting?
Methylation is a process where methyl groups are added to DNA, which can affect gene expression. Genomic imprinting is a phenomenon where certain genes are expressed based on whether they are inherited from the mother or father. Methylation plays a key role in genomic imprinting by regulating which parent's gene is expressed.
What chemical modificatin can shut down regions or newly replicated DNA?
The newly replicated DNA regions can be terminated by methylation chemical modification. Methylation is a methyl group alkylation of hydrogen atom replacement.
What does methylating DNA do?
DNA methylation essentially causes DNA to stick to the histones. RNA polymerase, an enzyme that splits DNA apart for transcription, cannot access methylated DNA, so it isn't used in protein synthesis. It is effectively silenced by the attached methyl group.
