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What else can I help you with?
Is doxorubicin is water soluble?
Doxorubicin has a solubility of 10mg in 1 ml of water, which should be warmed slightly.
How is bisulfite used?
Bisulfite is a type of salt, that can be used for a variety of purposes. It is commonly found in commercial wines and that is one of its most common uses. However, if Sodium Bisulfite can be used to kill germs and is in many household cleaners.
Can you Compare and contrast the three phrase changes on the molecular level?
Gene mutation involves changes in the DNA sequence, which can lead to altered protein production. Chromosomal changes involve modifications in the structure or number of chromosomes, impacting gene expression and cell function. Epigenetic changes can affect gene activity without altering the DNA sequence, influencing how genes are expressed through modifications like methylation or histone acetylation.
What is the net charge of DNA and how does it affect its interactions with other molecules?
The net charge of DNA is negative due to the phosphate groups in its structure. This negative charge can affect its interactions with other molecules by attracting positively charged molecules and repelling negatively charged ones. This charge plays a role in DNA's ability to bind to proteins and other molecules in processes such as gene expression and DNA replication.
What is the role of EtBr in electrophoresis?
Ethidium bromide interchalates with DNA. It doesn't affect electrophoresis, but it help visualise the DNA bands after electrophoresis. The EtBr that is bound to the DNA will fluoresce under ultraviolet light.
How does DNA methylation regulate gene activity?
DNA methylation is a process where methyl groups are added to specific regions of DNA, which can turn genes on or off. This modification can affect how genes are read and expressed, ultimately regulating gene activity.
What does Methylation of DNA prevent?
Methylation of DNA can regulate gene expression by preventing transcription factors from binding to specific regions of DNA, thereby silencing gene expression. Additionally, methylation of DNA can help stabilize the structure of chromosomes and maintain genomic stability.
DNA methylation in prokaryotes?
In prokaryotes, DNA methylation is a common epigenetic modification that involves the addition of a methyl group to cytosine bases in DNA. This process plays a role in regulating gene expression, DNA replication, and protection against foreign DNA such as viruses. DNA methylation patterns can vary between species and are important for controlling various cellular processes.
What protect the DNA?
Methylation protects DNA from nucleases, endonucleases
Where does methelation bind?
Methylation typically occurs on nitrogen or oxygen atoms in biological molecules such as proteins, DNA, and RNA. For example, in DNA, methylation often occurs on cytosine bases. Methylation can also occur on histone proteins associated with DNA to regulate gene expression.
What is the relationship between methylation and genomic imprinting?
Methylation is a process where methyl groups are added to DNA, which can affect gene expression. Genomic imprinting is a phenomenon where certain genes are expressed based on whether they are inherited from the mother or father. Methylation plays a key role in genomic imprinting by regulating which parent's gene is expressed.
Will methylation of DNA tend to turn a gene on or off?
off
What has the author Xiaolin Zhang written?
Xiaolin Zhang has written: 'Mutagenic mechanisms associated with DNA cytosine methylation, DNA base sequence context and DNA precursor pool asymmetry' -- subject(s): Mutagenesis, DNA, Nucleotide sequence, Methylation
How is DNA methylation utilized in the process of DNA repair?
DNA methylation plays a role in DNA repair by helping to identify and repair damaged DNA. It can signal where repairs are needed and regulate the activity of repair enzymes. This process helps maintain the integrity of the DNA and ensures proper functioning of the cell.
What chemical modificatin can shut down regions or newly replicated DNA?
The newly replicated DNA regions can be terminated by methylation chemical modification. Methylation is a methyl group alkylation of hydrogen atom replacement.
What is the chemical basis of gene imprinting?
Gene imprinting involves the addition of methyl groups to specific regions of DNA, a process known as DNA methylation. This methylation pattern is established during early development and can result in certain genes being silenced based on whether they were inherited from the mother or the father. It plays a critical role in regulating gene expression and cellular differentiation.
Why don't retrotransposons get smaller evrey time they insert into DNA?
Very high transposition is danger for genom. Because, the function of genom bereaks down.Both transposons and genom itself don not want it. Therefore, Transpozsons replicate themselver before methylation of DNA. after DNA replication, DNA is methylated. replication of transpositin occurs until methylation of DNA
