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What is the importance of Receptor-mediated Endocytosis in the genetic disorder Familial Hyper-Cholesterolemia?
In mammalian cells, the LDL (low density lipoprotein) receptor transports cholesterol into the cell via receptor-mediated endocytosis. The cholesterol is then used by the cell for various metabolic functions and the receptor is recycled to the plasma membrane.In patients suffering from Familial Hypercholesterolemia, the genes encoding the LDL receptor are mutated, as a result of which cholesterol is unable to bind to the LDL receptor. This leads to accumulation of cholesterol in the circulation, hence causing disease. Patients suffering from this disease are treated using drugs called Statins, which inhibit an important enzyme involved in cholesterol biosynthesis.
What factor influences the strength of the response in the receiving cell?
The strength of the response in a receiving cell is influenced by the number of ligand-receptor interactions that occur at the cell surface. The more interactions that take place, the stronger the signal generated within the cell. Other factors such as receptor density, affinity, and downstream signaling pathways also play a role in determining the strength of the response.
What term best describes the number of individuals of a given species per unit area?
Population density.
Density depends on what two physical properties?
Density depends on mass and volume. Mass is the amount of matter in an object, while volume is the amount of space it occupies. The formula for density is density = mass/volume.
The Temperature at which water possesses maximum density is?
The temperature at which water possesses maximum density is 4 degrees Celsius. At this temperature, water molecules are packed closely together, decreasing the volume per molecule and increasing the density.
What does the phrase density of receptor cells mean?
Density of receptor cells are the amount of receptor cells in a specific area of the body. This could be in the lips.
How Do You describe the shape of a data set?
You describe the shape, not of the data set, but of its density function.You describe the shape, not of the data set, but of its density function.You describe the shape, not of the data set, but of its density function.You describe the shape, not of the data set, but of its density function.
How do geographer describe location?
Geographers describe location in terms of absolute location, which specifies a point on the Earth's surface using coordinates, and relative location, which describes a place in relation to other landmarks or geographic features. They may also consider location in terms of its physical characteristics, such as climate, landforms, and vegetation, or its human-made attributes, such as population density and infrastructure.
Describe the density of the vinegar compared to the density of the oil?
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What is the population density of France?
how would you describe the population density of france
Is it true that the density of a sample depends on it location on earth?
No, the density of a sample does not depend on its location on Earth. Density is a physical property of a substance that remains constant regardless of its location. However, the gravitational force acting on an object can affect its weight, which may give the appearance of a change in density when in fact it remains the same.
Why people have a different taste threshold from someone else?
why people have a different taste threshold from someone else or even have different density of receptors whithin our body? The receptor density is different. I think it's due to genetics bumping into environmental history. For example, I'd bet that flame swallowers have a reduced receptor density. Some people can taste X while others can't, and often the difference is due to genetics.
Volume and density describe what part of an object?
Mass
What is the word used to describe how thick an oil is?
density
Describe the population density and distribution in Italy?
Uneven distribution
What units do you normally use to describe the density of a liquid?
viscosity
What is the density of of table salt?
That's the bulk density. Crystal density is 2.16 ish g/ml.Measuring density of such a small item can be difficult. The density of table salt is 2.17 grams per cubic centimeter.
